868742-05-6

Basic information

• Product Name: C₃₅H₂₆F₃N₅O
• Synonyms: C₃₅H₂₆F₃N₅O
• CAS NO: 868742-05-6
• Molecular Weight: 589.62
• Mol File: 868742-05-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₅H₂₆F₃N₅O(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₅H₂₆F₃N₅O(868742-05-6)
• EPA Substance Registry System: C₃₅H₂₆F₃N₅O(868742-05-6)

Safety Data

• Hazardous Substances Data: 868742-05-6(Hazardous Substances Data)

Upstream product

• 354-38-1 2,2,2-trifluoroacetamide 
• 124750-51-2 N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole 

Downstream Products

• 147225-68-1 (2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methanamine 

Relevant articles and documents

NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY

Compounds which may be represented by the general formula (I) shown below and in which: R1 is a group independently selected from among: CHO, -COOH, -CH2OH R2 is hydrogen or a linear or branched C1-C6 alkyl group R3 is hydrogen or a halogen group selected from among Cl and Br R4 is a linear or branched C3-C5 alkyl group and the pharmaceutically acceptable salts thereof such as the sodium or potassium salt. The compounds exhibit potent and selective All antagonist activity and are useful for the treatment of any disorders in which elevated synthesis of All or overexpression of the AT1 receptor may play a primary pathological role, as in the case of arterial hypertension, congestive cardiac insufficiency, platelet aggregation and disorders associated therewith such as for example myocardial and cerebral infarction, renal ischaemia, venous and arterial thrombosis, peripheral vasculopathy, pulmonary hypertension, diabetes mellitus, diabetic neuropathy, glaucoma and diabetic retinopathy.