86917-57-9

Basic information

• Product Name: (D-PRO4,D-TRP7,9,10)-SUBSTANCE P (4-11)
• Synonyms: H-D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2;(D-PRO4,D-TRP7,9,10)-SUBSTANCE P (4-11);D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-MET-NH2;DPRO-GLN-GLN-DTRP-PHE-DTRP-DTRP-MET-NH2;(D-pro4,D-trp7,9,10)-substance P*fragment 4-11;Substance P, fragment 4-11, [D-Pro4, D-Trp7,9,10];D-Pro-L-Gln-L-Gln-D-Trp-L-Phe-D-Trp-D-Trp-L-Met-NH2;D-Pro-L-Glu(NH2)-L-Glu(NH2)-D-Trp-L-Phe-D-Trp-D-Trp-L-Met-NH2
• CAS NO: 86917-57-9
• Molecular Formula: C62H74N14O10S
• Molecular Weight: 1207.4
• Mol File: 86917-57-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: (D-PRO4,D-TRP7,9,10)-SUBSTANCE P (4-11)(CAS DataBase Reference)
• NIST Chemistry Reference: (D-PRO4,D-TRP7,9,10)-SUBSTANCE P (4-11)(86917-57-9)
• EPA Substance Registry System: (D-PRO4,D-TRP7,9,10)-SUBSTANCE P (4-11)(86917-57-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 86917-57-9(Hazardous Substances Data)

Usage

General Description

(D-PRO4,D-TRP7,9,10)-SUBSTANCE P (4-11), also known as SP-D, is a synthetic analog of the neuropeptide substance P, which plays a role in pain transmission and inflammatory processes. This chemical is designed to be more stable and potent than the natural form, making it a promising candidate for therapeutic applications. It has been studied for its potential use in the treatment of chronic pain conditions, inflammation-related disorders, and neurological diseases. SP-D has shown promising results in preclinical studies, demonstrating its ability to modulate pain perception and reduce inflammation. Additionally, it has been investigated for its potential neuroprotective effects and its role in regulating mood and behavior. Overall, SP-D shows potential as a valuable tool for understanding the role of substance P in various physiological and pathological processes, and it holds promise for the development of novel therapeutics for a range of conditions.

InChI:InChI=1/C62H74N14O10S/c1-87-27-25-45(55(65)79)70-60(84)50(29-36-32-67-42-17-8-5-14-39(36)42)76-62(86)52(31-38-34-69-44-19-10-7-16-41(38)44)75-59(83)49(28-35-12-3-2-4-13-35)73-61(85)51(30-37-33-68-43-18-9-6-15-40(37)43)74-58(82)48(22-24-54(64)78)72-57(81)47(21-23-53(63)77)71-56(80)46-20-11-26-66-46/h2-10,12-19,32-34,45-52,66-69H,11,20-31H2,1H3,(H2,63,77)(H2,64,78)(H2,65,79)(H,70,84)(H,71,80)(H,72,81)(H,73,85)(H,74,82)(H,75,83)(H,76,86)/t45-,46+,47-,48-,49-,50+,51+,52+/m0/s1