86952-89-8

Basic information

• Product Name: 4-(oxiran-2-yl)phenyl acetate
• Synonyms: 4-(oxiran-2-yl)phenyl acetate
• CAS NO: 86952-89-8
• Molecular Weight: 178.188
• Mol File: 86952-89-8.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 4-(oxiran-2-yl)phenyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(oxiran-2-yl)phenyl acetate(86952-89-8)
• EPA Substance Registry System: 4-(oxiran-2-yl)phenyl acetate(86952-89-8)

Safety Data

• Hazardous Substances Data: 86952-89-8(Hazardous Substances Data)

Upstream product

• 2628-16-2 p-acetoxystyrene 
• 878-00-2 4-formylphenyl acetate 
• 593-71-5 Chloroiodomethane 
• 2181-42-2 trimethylsulphonium iodide 

Downstream Products

• 2345-34-8 4-acetyloxy-benzoic acid 
• 439584-65-3 4-(1,2-dihydroxyethyl)phenyl acetate 
• 99-96-7 4-hydroxy-benzoic acid 
• 1245926-99-1 C₁₀H₁₁⁽²⁾HO₃ 
• 60037-43-6 2-(4-acetoxyphenyl)ethanol 
• 2628-16-2 p-acetoxystyrene 

Relevant articles and documents

A new and efficient methodology for olefin epoxidation catalyzed by supported cobalt nanoparticles

A new heterogeneous catalytic system consisting of cobalt nanoparticles (CoNPs) supported on MgO and tert-butyl hydroperoxide (TBHP) as oxidant is presented. This CoNPs@MgO/t-BuOOH catalytic combination allowed the epoxidation of a variety of olefins with good to excellent yield and high selectivity. The catalyst preparation is simple and straightforward from commercially available starting materials and it could be recovered and reused maintaining its unaltered high activity.

Remarkable increase in the rate of the catalytic epoxidation of electron deficient styrenes through the addition of Sc(OTf)3 to the MnTMTACN catalyst

The effect of Lewis acids on the catalytic activity of [Mn2(μ-O)3(TMTACN)2](PF6)2 in the epoxidation of styrenes using hydrogen peroxide as the oxidant has shown that the addition of Sc(OTf)3 at low catalytic loading results in a very significant increase in the efficiency of the catalyst and a reduction of the reaction time to only 3 minutes in most cases.

The Activation of Carboxylic Acids via Self-Assembly Asymmetric Organocatalysis: A Combined Experimental and Computational Investigation

The heterodimerizing self-assembly between a phosphoric acid catalyst and a carboxylic acid has recently been established as a new activation mode in Br?nsted acid catalysis. In this article, we present a comprehensive mechanistic investigation on this activation principle, which eventually led to its elucidation. Detailed studies are reported, including computational investigations on the supramolecular heterodimer, kinetic studies on the catalytic cycle, and a thorough analysis of transition states by DFT calculations for the rationalization of the catalyst structure-selectivity relationship. On the basis of these investigations, we developed a kinetic resolution of racemic epoxides, which proceeds with high selectivity (up to s = 93), giving the unreacted epoxides and the corresponding protected 1,2-diols in high enantiopurity. Moreover, this approach could be advanced to an unprecedented stereodivergent resolution of racemic α-chiral carboxylic acids, thus providing access to a variety of enantiopure nonsteroidal anti-inflammatory drugs and to α-amino acid derivatives.