86969-37-1

Basic information

• Product Name: 1-(3-METHYLPHENYL)-2-NITROPROPENE
• Synonyms: 1-methyl-3-[(1Z)-2-nitroprop-1-en-1-yl]benzene
• CAS NO: 86969-37-1
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.2
• Mol File: 86969-37-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(3-METHYLPHENYL)-2-NITROPROPENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-METHYLPHENYL)-2-NITROPROPENE(86969-37-1)
• EPA Substance Registry System: 1-(3-METHYLPHENYL)-2-NITROPROPENE(86969-37-1)

Safety Data

• Hazardous Substances Data: 86969-37-1(Hazardous Substances Data)

Usage

Description

1-(3-METHYLPHENYL)-2-NITROPROPENE, with the molecular formula C10H11NO2, is a nitroalkene compound characterized by a nitro group attached to the second carbon of a propene chain and a 3-methylphenyl group attached to the first carbon. This chemical compound is widely recognized in the fields of organic and medicinal chemistry for its versatile applications and potential pharmacological properties.

Uses

Used in Organic Chemistry:
1-(3-METHYLPHENYL)-2-NITROPROPENE is used as a reagent for the synthesis of other organic compounds, leveraging its unique structure and reactivity to facilitate various chemical reactions and the creation of a diverse range of products.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(3-METHYLPHENYL)-2-NITROPROPENE is utilized for its potential pharmacological properties. Researchers have studied its interactions with biological systems, exploring its possible applications in the development of new drugs and therapies.
Used in Pharmaceutical Synthesis:
1-(3-METHYLPHENYL)-2-NITROPROPENE also serves as a precursor in the synthesis of various pharmaceuticals and other chemical products. Its unique structure makes it a valuable building block for creating complex molecules with specific therapeutic effects.
Overall, 1-(3-METHYLPHENYL)-2-NITROPROPENE is a versatile compound with significant applications across different industries, including organic chemistry, medicinal chemistry, and pharmaceutical synthesis. Its unique structure and reactivity contribute to its wide range of uses and potential for further research and development.

Upstream product

• 79-24-3 Nitroethane 
• 620-23-5 m-tolyl aldehyde 

Downstream Products

• 18826-61-4 3-methylphenylacetone 
• 1442645-55-7 C₂₁H₂₁NO₂ 
• 1374229-48-7 1-(2,5-dimethyl-4-m-tolylfuran-3-yl)ethanone 
• 1374229-39-6 methyl 2,5-dimethyl-4-m-tolyl-1H-pyrrole-3-carboxylate 
• 1374229-49-8 ethyl 2,5-dimethyl-4-m-tolylfuran-3-carboxylate 
• 921-11-9 2,3,4-pentanetrione 
• 109704-01-0 Methyl<2,5-dimethyl-4-(3-tolyl)-3-pyrrolyl>keton 
• 29865-51-8 1-(3'-methylphenyl)-2-nitropropane 
• 588-06-7 1-(3-toluyl)-2-propylamine 

Relevant articles and documents

Iron-catalyzed tandem one-pot addition and cyclization of the blaise reaction intermediate and nitroolefins: Synthesis of substituted NH-pyrroles from nitriles

The iron-catalyzed addition and cyclization of the Blaise reaction intermediate and nitroolefins to synthesize highly functionalized NH-pyrroles in a tandem one-pot manner from nitriles has been developed. This reaction shows good functional group tolerance and affords a broad spectrum of substituted NH-pyrroles in good yields. Copyright

ACETONYLATION AROMATIQUE HOMOLYTIQUE

Treatment of monosubstituted benzene derivatives with acetone and manganese(III) acetate in acetic acid gave rise to products of homolytic aromatic substitution in fairly good yields and high purity except for toluene.Isomer distribution, relative rates and partial rate factors were determeined for toluene, anisole, chlorobenzene, bromobenzene and benzonitrile.A Hammet plot of the logarithm of the partial rate factors for meta and para positions vs. ?-constants gave a slope ρ of -1.74 +/- 0.40 (confidence interval at the level 95percent).When using ?+-constants the slope becomes ρ+ = -1.25 +/- 0.36.The negative velues of ρ and ρ+ indicated that the acetonyl radical has an appreciable electrophilic character.