869718-80-9 Usage
Description
MPEG8-N3, also known as m-PEG8-azide, is a monodisperse PEG linker that contains an azide group. It is reactive with alkyne, BCN, and DBCO through Click Chemistry, resulting in a stable triazole linkage. This unique property makes it a versatile building block for the synthesis of various bioconjugates and materials.
Uses
Used in Bioconjugation:
MPEG8-N3 is used as a PEG linker for bioconjugation applications. Its azide group allows for efficient and site-specific conjugation to alkyne-containing biomolecules, such as peptides, proteins, and oligonucleotides, through Click Chemistry. This enables the formation of stable triazole linkages, improving the stability and solubility of the resulting bioconjugates.
Used in Drug Delivery Systems:
In the pharmaceutical industry, MPEG8-N3 is used as a PEG linker for the development of drug delivery systems. Its ability to form stable triazole linkages with drug molecules or nanoparticles allows for the creation of targeted and controlled release systems, enhancing the therapeutic efficacy and reducing side effects of various drugs.
Used in Materials Science:
In the field of materials science, MPEG8-N3 is used as a PEG linker for the synthesis of functional materials. Its compatibility with Click Chemistry enables the fabrication of well-defined and stimuli-responsive materials with applications in areas such as sensors, actuators, and self-healing materials.
Overall, MPEG8-N3 is a versatile and valuable building block in various industries, including pharmaceuticals, bioconjugation, and materials science, due to its unique reactivity and ability to form stable triazole linkages through Click Chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 869718-80-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,7,1 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 869718-80:
(8*8)+(7*6)+(6*9)+(5*7)+(4*1)+(3*8)+(2*8)+(1*0)=239
239 % 10 = 9
So 869718-80-9 is a valid CAS Registry Number.
869718-80-9Relevant articles and documents
Synthesis of branched monodisperse oligoethylene glycols and 19f mri-traceable biomaterials through reductive dimerization of azides
Chen, Shizhen,Jiang, Zhong-Xing,Li, Yu,Yang, Hao,Yang, Zhigang,Yuan, Yuan,Zhang, Huaibin,Zhang, Jing,Zhou, Xin
, p. 6778 - 6787 (2020/06/08)
Multifunctionalized and branched M-OEGs represent valuable PEGylation agents, linkers, and scaffolds in biomedicine. However, the tedious synthesis limited their availability and application. We herein present an azide reductive dimerization method for the convenient synthesis of aza-M-OEGs and derivatives, which provides easy access to a variety of multifunctionalized and branched M-OEGs in one step. With this method, hexa-arm M-OEGs with 54 symmetrical fluorines were synthesized in two steps as a water-soluble, self-assemble, 19F MRI sensitive, and biocompatible dendritic biomaterial.
TREATMENT OF MYOPIA
-
, (2010/02/14)
The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment and/or prevention of myopia. An activating energy source is utilize
