870087-36-8 Usage
General Description
Apilimod mesylate is a small molecule inhibitor of the IL-12/IL-23 pathways that has shown promising results in preclinical and clinical studies for the treatment of various autoimmune diseases, including rheumatoid arthritis and multiple sclerosis. It inhibits the production of pro-inflammatory cytokines, reduces the activation of immune cells, and suppresses the activity of dendritic cells, which play a key role in the immune response. Apilimod mesylate also has the potential to modulate the activity of regulatory T cells, which can help restore balance to the immune system and alleviate symptoms of autoimmune diseases. Its mechanism of action and promising results in early clinical trials make it a potentially valuable therapeutic option for various autoimmune conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 870087-36-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,0,0,8 and 7 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 870087-36:
(8*8)+(7*7)+(6*0)+(5*0)+(4*8)+(3*7)+(2*3)+(1*6)=178
178 % 10 = 8
So 870087-36-8 is a valid CAS Registry Number.
870087-36-8Relevant articles and documents
PROCESS FOR PREPARING MESYLATE SALTS OF IL-12 INHIBITORY COMPOUNDS
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Page/Page column 158, (2008/06/13)
This invention relates to a method of preparing mesylate salts of compounds that inhibit IL-12, IL-23 and/or IL-27 production.
