87014-71-9

Basic information

• Product Name: (±)-trans-2-(dimethylamino)cyclopentanol
• Synonyms: (±)-trans-2-(dimethylamino)cyclopentanol
• CAS NO: 87014-71-9
• Molecular Weight: 129.202
• Mol File: 87014-71-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (±)-trans-2-(dimethylamino)cyclopentanol(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-trans-2-(dimethylamino)cyclopentanol(87014-71-9)
• EPA Substance Registry System: (±)-trans-2-(dimethylamino)cyclopentanol(87014-71-9)

Safety Data

• Hazardous Substances Data: 87014-71-9(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 31775-67-4 (±)-trans-2-aminocyclopentanol hydrochloride 

Downstream Products

• 167280-11-7 nitrile of 2-(N,N-dimethylamino)cyclopentanecarboxylic acid 
• 67440-68-0 trans-N,N-dimethyl-N'-<4-(trifluoromethyl)phenyl>-1,2-cyclopentanediamine 

Relevant articles and documents

Cycloalkyl and heterocycloalkyl inhibitors as well as preparation method and application thereof

The invention relates to cycloalkyl and heterocycloalkyl inhibitors as well as a preparation method and application thereof. Specifically, the compounds disclosed by the invention have a structure as shown in a formula (I). The invention also discloses a preparation method of the compounds and application of the compounds as KRASG12C inhibitors. The compounds have a good selective inhibition effect on KRASG12C, and have better pharmacodynamic and pharmacokinetic properties and lower toxic and side effects.