870861-85-1Relevant articles and documents
Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2
Grimstrup, Marie,Rist, ystein,Receveur, Jean-Marie,Frimurer, Thomas M.,Ulven, Trond,Mathiesen, Jesper M.,Kostenis, Evi,Hoegberg, Thomas
scheme or table, p. 1181 - 1185 (2010/06/15)
Structure-activity relationships have been established by exploring the eastern and western side of 5-thiazolyleacetic acids as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells) antagonists. Benzhydryl motifs in the 2-position of