872168-54-2Relevant articles and documents
Novel steroid mimics directed towards the estradiol skeleton
Bridgeman, Eve,Cavill, Julie L.,Schofield, Daniel J.,Wilkins, Derek S.,Tomkinson, Nicholas C. O.
, p. 8521 - 8524 (2007/10/03)
A series of non-symmetrical tri- and tetra-substituted ureas have been prepared to mimic the rigid tetracyclic core of estradiol. Tetra-substituted ureas were prepared by a five-step protocol, involving activation and displacement of a carbonyldiimidazole