872706-97-3

Basic information

• Product Name: 2-Pyridinamine,4-(chloromethyl)-(9CI)
• Synonyms: 2-Pyridinamine,4-(chloromethyl)-(9CI);4-(ChloroMethyl)pyridin-2-aMine;4-(Chloromethyl)-2-pyridinamine
• CAS NO: 872706-97-3
• Molecular Formula: C₆H₇ClN₂
• Molecular Weight: 142.588
• Product Categories: PYRIDINE
• Mol File: 872706-97-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 294.6°C at 760 mmHg
• Flash Point: 132°C
• Appearance: /
• Density: 1.265g/cm³
• Vapor Pressure: 0.00161mmHg at 25°C
• Refractive Index: 1.596
• Storage Temp.: 2-8°C
• PKA: 6.30±0.11(Predicted)
• CAS DataBase Reference: 2-Pyridinamine,4-(chloromethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinamine,4-(chloromethyl)-(9CI)(872706-97-3)
• EPA Substance Registry System: 2-Pyridinamine,4-(chloromethyl)-(9CI)(872706-97-3)

Safety Data

• Hazardous Substances Data: 872706-97-3(Hazardous Substances Data)

Usage

General Description

2-Pyridinamine, 4-(chloromethyl)-(9CI) is a chemical compound with the molecular formula C6H6ClN3. It is an amine derivative with a pyridine ring and a chloromethyl group attached to the 4th carbon position. 2-Pyridinamine,4-(chloromethyl)-(9CI) is a white to light beige crystalline powder with a melting point of around 156-160°C. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. The chloromethyl group on the pyridinamine molecule makes it a versatile building block for the preparation of various functionalized derivatives with potential biological and industrial applications. However, it is important to handle this compound with caution as it may pose hazards if not used properly.

InChI:InChI=1/C6H7ClN2/c7-4-5-1-2-9-6(8)3-5/h1-3H,4H2,(H2,8,9)

Upstream product

• 1186663-31-9 4-(chloromethyl)pyridine-2-amine hydrochloride 
• 105250-17-7 2-amino-4-hydroxymethylpyridine 
• 672324-82-2 tert-butyl 4-(chloromethyl)pyridin-2-ylcarbamate 
• 53547-60-7 4-methyl-2-pyridinecarbaldehyde 

Downstream Products

• 872708-84-4 2-{[(2-aminopyridin-4-yl)methyl]amino}-N-(2,2-difluoro-1,3-benzodioxol-5-yl)benzamide 
• 105250-17-7 2-amino-4-hydroxymethylpyridine 
• 1313726-28-1 7-(chloromethyl)-[1,2,4]triazolo[1,5-a]pyridine 
• 872706-98-4 N-(4-(chloromethyl)pyridin-2-yl)acetamide 

Relevant articles and documents

Preparation method of 2-aminopyridine-4-methyl alcohol intermediate

The invention discloses a preparation method of a 2-aminopyridine-4-methyl alcohol intermediate. The preparation method includes the following steps of adopting 4-methylpyridine-2-formaldehyde as a raw material and making the raw material subjected to a chlorine substitute reaction to convert methyl into chloromethyl; then conducting an oxidizing reaction to convert formyl into carboxyl; then making the raw material react with triethylamine and DPPA to convert carboxyl into amino and oxidizing chloromethyl into hydroxymethyl to obtain 2-aminopyridine-4-methyl alcohol. The preparation method issimple in operation, mild in condition and high in product purity and product yield and generates few by-products.

1-METHYL-1H-PYRAZOLE-4-CARBOXAMIDES USEFUL AS CANCER CHEMOTHERAPEUTIC AGENTS

This invention relates to novel 1 -Methyl- lH-pyrazole-4-carboxamide compounds, pharmaceutical compositions containing such compounds, and the use of those compounds or compositions as cancer chemotherapeutic agents.

2-AMINOTHIOPHENECARBOXAMIDES USEFUL AS CANCER CHEMOTHERAPEUTIC AGENTS

This invention relates to novel 2-aminothiophenecarboxamide compounds, pharmaceutical compositions containing such compounds, and the use of those compounds or compositions as cancer chemotherapeutic agents.