873381-94-3Relevant articles and documents
Benzofuran synthesis via copper-mediated oxidative annulation of phenols and unactivated internal alkynes
Zhu, Ruyi,Wei, Jiangbo,Shi, Zhangjie
, p. 3706 - 3711 (2013/11/19)
The first example of copper-mediated oxidative annulation of phenols and unactivated internal alkynes to afford benzofuran derivatives was reported. Various phenols and unactivated internal alkynes were successfully employed. Mechanistic studies disclosed a new strategy on annulations of alkynes with phenols through reversible electrophilic carbocupration of phenol followed by alkyne insertion and cyclization.