873811-55-3 Usage
Description
(2E)-3-[4-(2-AMINO-2-OXOETHOXY)PHENYL]ACRYLIC ACID, also known as ethacrynic acid, is a loop diuretic medication that functions by inhibiting the reabsorption of sodium and chloride ions in the kidneys. This action leads to increased urine production and reduced fluid retention, making it a valuable treatment for high blood pressure and edema. Ethacrynic acid is structurally similar to other loop diuretics like furosemide and bumetanide, yet it possesses a distinct mechanism of action.
Used in Pharmaceutical Industry:
(2E)-3-[4-(2-AMINO-2-OXOETHOXY)PHENYL]ACRYLIC ACID is used as a diuretic medication for the treatment of high blood pressure and fluid retention. It is particularly beneficial for patients with heart failure, kidney disease, and liver disease, as it helps to alleviate edema and lower blood pressure.
Used in Cardiology:
In the field of cardiology, (2E)-3-[4-(2-AMINO-2-OXOETHOXY)PHENYL]ACRYLIC ACID is used as a therapeutic agent to manage heart failure by reducing the workload on the heart through decreased fluid retention and lowering blood pressure.
Used in Nephrology:
(2E)-3-[4-(2-AMINO-2-OXOETHOXY)PHENYL]ACRYLIC ACID is used in nephrology to treat kidney disease by promoting the removal of excess fluid and sodium from the body, which can help to alleviate the symptoms and complications associated with kidney dysfunction.
Used in Hepatology:
In hepatology, (2E)-3-[4-(2-AMINO-2-OXOETHOXY)PHENYL]ACRYLIC ACID is utilized to address liver disease by reducing fluid buildup and managing blood pressure, which can be particularly important in cases where liver function is compromised and the body's ability to regulate fluid balance is impaired.
Check Digit Verification of cas no
The CAS Registry Mumber 873811-55-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,3,8,1 and 1 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 873811-55:
(8*8)+(7*7)+(6*3)+(5*8)+(4*1)+(3*1)+(2*5)+(1*5)=193
193 % 10 = 3
So 873811-55-3 is a valid CAS Registry Number.
873811-55-3Relevant articles and documents
Competitive formation of β-amino acids, propenoic, and ylidenemalonic acids by the Rodionov reaction from malonic acid, aldehydes, and ammonium acetate in alcoholic medium
Lebedev,Lebedeva,Sheludyakov,Kovaleva,Ustinova,Kozhevnikov
, p. 1113 - 1124 (2007/10/03)
The Rodionov reaction of 49 available aliphatic and aromatic aldehydes with malonic acid and ammonium acetate in alcoholic medium, resulting in formation of β-amino acids, propenoic, and ylidenemalonic acids, was studied. Certain regioselectivity regularities of the reaction were revealed. Among the variety of ketones studied, cyclohexanone is the only whose reaction yields a β-amino acid. Unusual dehydrofluorination of 6-chloro-2-fluorocinnamic acid under the Rodionov reaction was discovered. 2005 Pleiades Publishing, Inc.
