87384-53-0

Basic information

• Product Name: 3-carbamoyl-1-(2,4,6-trimethylbenzyl)pyridinium chloride
• Synonyms: 3-carbamoyl-1-(2,4,6-trimethylbenzyl)pyridinium chloride
• CAS NO: 87384-53-0
• Molecular Formula: C16H19ClN2O
• Molecular Weight: 291
• Mol File: 87384-53-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-carbamoyl-1-(2,4,6-trimethylbenzyl)pyridinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-carbamoyl-1-(2,4,6-trimethylbenzyl)pyridinium chloride(87384-53-0)
• EPA Substance Registry System: 3-carbamoyl-1-(2,4,6-trimethylbenzyl)pyridinium chloride(87384-53-0)

Safety Data

• Hazardous Substances Data: 87384-53-0(Hazardous Substances Data)

Upstream product

• 98-92-0 nicotinamide 
• 1585-16-6 2-chloromethyl-1,3,5-trimethylbenzene 

Relevant articles and documents

The use of immobilized enzymes in organic synthesis. Part 8. Oxidation of 1-aryl-3-carbamoylpyridinium chlorides by rabbit liver aldehyde oxidase and bovine milk xanthine oxidase

Oxidation of 1-aryl-3-carbamoylpyridinium chlorides with immobilized rabbit liver aldehyde oxidase gave predominantly 1-aryl-1,6-dihydro-6-oxo-3-pyridinecarboxamides, together with the corresponding 1-aryl-1,4-dihydro-4-oxo-3-pyridinecarboxamides.In general, the site of oxidation by this enzyme is determined by steric factors.The rate of oxidation by free aldehyde oxidase is very sensitive to electronic effects.A more electron-withdrawing aryl substituent increases the reaction rate for oxidation to 6-oxo product.Consequently, a positive ρ value of about 3.6 was calculated for free aldehyde oxidase.Oxidation of these compounds by bovinr milk xanthine oxidase yielded mainly 4-oxo products.Preparative-scale reactions with both free and immobilized xanthine oxidase gave low product yields.The oxidation rate of free xanthine oxidase is only slightly affected by substituents in the aryl group.