87394-55-6

Basic information

• Product Name: 1-(3-CHLOROPYRIDIN-2-YL)PIPERAZINE
• Synonyms: 1-(3-Chloro-2-pyridyl)piperazine;1-(3-Chloro-2-pyridinyl)-piperazine;Piperazine, 1-(3-chloro-2-pyridinyl)-
• CAS NO: 87394-55-6
• Molecular Formula: C₉H₁₂ClN₃
• Molecular Weight: 197.66
• Product Categories: pharmacetical;alkyl chloride
• Mol File: 87394-55-6.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 331.4 °C at 760 mmHg
• Flash Point: 154.2 °C
• Appearance: /
• Density: 1.213 g/cm³
• Vapor Pressure: 0.000156mmHg at 25°C
• Refractive Index: 1.561
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(3-CHLOROPYRIDIN-2-YL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-CHLOROPYRIDIN-2-YL)PIPERAZINE(87394-55-6)
• EPA Substance Registry System: 1-(3-CHLOROPYRIDIN-2-YL)PIPERAZINE(87394-55-6)

Safety Data

• Hazardous Substances Data: 87394-55-6(Hazardous Substances Data)

Usage

General Description

1-(3-Chloropyridin-2-yl)piperazine is a chemical compound that belongs to the class of piperazine derivatives. It is a heterocyclic compound that contains both a piperazine ring and a chloropyridine ring. This chemical is often used in the field of medicinal chemistry as a building block for the synthesis of various pharmaceuticals and bioactive compounds. Its unique structure and reactivity make it a valuable tool for drug discovery and development. Additionally, it has been studied for its potential use in the treatment of various diseases and disorders. However, like all chemical compounds, 1-(3-Chloropyridin-2-yl)piperazine requires careful handling and proper safety precautions due to its potential health hazards and reactivity.

InChI:InChI=1/C9H12ClN3/c10-8-2-1-3-12-9(8)13-6-4-11-5-7-13/h1-3,11H,4-7H2

Upstream product

• 110-85-0 piperazine 
• 2402-77-9 2,3-dichloro-pyridine 
• 683240-45-1 tert-butyl 4-(3-chloropyridin-2-yl)piperazine-1-carboxylate 
• 71-36-3 butan-1-ol 

Downstream Products

• 1202247-73-1 C₂₂H₂₀ClN₃O₂ 
• 1202247-63-9 C₂₀H₂₄ClN₃O₂ 
• 1202247-69-5 C₁₆H₁₅Cl₂N₃O₂ 
• 1202247-71-9 C₁₆H₁₅Cl₂N₃O₂ 
• 1202247-65-1 C₁₇H₁₅ClF₃N₃O₂ 
• 1202247-61-7 C₂₀H₂₄ClN₃O₂ 
• 1202247-67-3 C₁₇H₁₅ClF₃N₃O₂ 

Relevant articles and documents

PYRROLE mTORC INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

Substituted indole compound and method and use thereof

The invention provides a new indole compound, pharmaceutically acceptable salts and medicinal preparations thereof, and a use of the new indole compound in selective inhibition of 5-hydroxytryptamine reuptake and /or excitation of a 5-HT1A receptor. The invention also relates to medicinal compositions comprising the compounds, and a method for treating the central nervous system dysfunction of mammals, especially humans by using the medicinal compositions.

GLYCINE COMPOUND

[Problem] The present invention provides a compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases. [Means for Solution] The present inventors have conducted intensive studies on a compound having a VAP-1 inhibitory activity, and as a result, they have found that a compound of the present invention or a salt thereof exhibits an excellent VAP-1 inhibitory activity and is useful for preventing and/or treating VAP-1-related diseases, in particular, diabetic nephropathy or diabetic macular edema, thereby completing the present invention. The present invention further relates to a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases, which comprises the compound of the present invention or a salt thereof, and an excipient.