87394-87-4

Basic information

• Product Name: 8-HYDROXY-DPAT HYDROBROMIDE
• Synonyms: 8-OH-DPAT HBR;[+/-]-8-OH-DPAT HYDROBROMIDE;(+/-)-8-HYDROXYDIPROPYLAMINOTETRALIN HBR;8-HYDROXY-DPAT HBR;(+/-)-8-HYDROXY-DPAT HYDROBROMIDE;8-HYDROXY-DPAT HYDROBROMIDE;(+/-)-8-HYDROXY-2-DIPROPYLAMINOTETRALIN HYDROBROMIDE;(+/-)-8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN HYDROBROMIDE
• CAS NO: 87394-87-4
• Molecular Formula: C16H26BrNO
• Molecular Weight: 328.29
• Product Categories: Amino Alcohols;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 87394-87-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-HYDROXY-DPAT HYDROBROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-HYDROXY-DPAT HYDROBROMIDE(87394-87-4)
• EPA Substance Registry System: 8-HYDROXY-DPAT HYDROBROMIDE(87394-87-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 87394-87-4(Hazardous Substances Data)

Usage

Description

8-HYDROXY-DPAT HYDROBROMIDE, also known as (±)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide, is a potent and selective 5-hydroxytryptamine (5HT1A)-receptor agonist. It is a synthetic compound that plays a significant role in the field of pharmacology, particularly in the study of serotonin receptors.
Used in Pharmaceutical Research:
8-HYDROXY-DPAT HYDROBROMIDE is used as a pharmacological standard for [application reason] in the development and testing of new drugs targeting the 5HT1A receptor. Its high selectivity and potency make it an ideal tool for studying the effects of 5HT1A receptor agonists on various physiological and pathological processes.
Used in Neuropharmacology:
In the field of neuropharmacology, 8-HYDROXY-DPAT HYDROBROMIDE is used as a research compound for [application reason] investigating the role of 5HT1A receptors in mood disorders, anxiety, and other central nervous system functions. Its ability to selectively activate these receptors allows researchers to gain insights into the mechanisms underlying the therapeutic effects of 5HT1A agonists.
Used in Drug Development:
8-HYDROXY-DPAT HYDROBROMIDE is used as a lead compound for [application reason] in the development of novel therapeutic agents with potential applications in the treatment of depression, anxiety, and other mood-related disorders. Its selectivity for the 5HT1A receptor makes it a valuable starting point for the design of new drugs with improved efficacy and safety profiles.
Used in Toxicology Studies:
In toxicology research, 8-HYDROXY-DPAT HYDROBROMIDE is used as a reference substance for [application reason] evaluating the safety and potential side effects of new drugs targeting the 5HT1A receptor. Its well-defined pharmacological properties enable researchers to assess the risk-benefit ratio of these compounds and ensure their safety for clinical use.

Biochem/physiol Actions

Selective 5-HT1 agonist with high affinity for subtype 5-HT1A receptor.

Upstream product

• 3894-47-1 (8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine; hydrochloride 
• 81185-18-4 Benzyl-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine 
• 81185-19-5 N-benzyl-8-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine 
• 78095-31-5 (8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine; hydrochloride 
• 3894-47-1 (8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine; hydrochloride 
• 81185-18-4 Benzyl-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine 
• 78095-31-5 (8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine; hydrochloride 

Relevant articles and documents

8-Hydroxy-2-(di-n-propylamino)tetralin, a New Centrally Acting 5-Hydroxytryptamine Receptor Agonist

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