87434-76-2

Basic information

• Product Name: benzyl 3,5-bis(2-chloroethyl)-1-(2-(methoxycarbonyl)ethyl)-1',2,4,6-tetramethyltripyrrin-a-6'-carboxylate hydrobromide
• CAS NO: 87434-76-2
• Molecular Weight: 705.519
• Mol File: 87434-76-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl 3,5-bis(2-chloroethyl)-1-(2-(methoxycarbonyl)ethyl)-1',2,4,6-tetramethyltripyrrin-a-6'-carboxylate hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 3,5-bis(2-chloroethyl)-1-(2-(methoxycarbonyl)ethyl)-1',2,4,6-tetramethyltripyrrin-a-6'-carboxylate hydrobromide(87434-76-2)
• EPA Substance Registry System: benzyl 3,5-bis(2-chloroethyl)-1-(2-(methoxycarbonyl)ethyl)-1',2,4,6-tetramethyltripyrrin-a-6'-carboxylate hydrobromide(87434-76-2)

Safety Data

• Hazardous Substances Data: 87434-76-2(Hazardous Substances Data)

Upstream product

• 18818-25-2 methyl 3-(5-formyl-2,4-dimethyl-1H-pyrrol-3-yl)propanoate 
• 54605-90-2 tert-butyl 5'-<(benzyloxy)carbonyl>-3',4-bis(2-chloroethyl)-3,4'-dimethyldipyrrylmethane-5-carboxylate 

Relevant articles and documents

New Efficient Total Syntheses of Derivatives of Protoporphyrin-IX Bearing Deuterated Methyl Groups

New total syntheses of hemins which are regioselectively deuterated in the 1,5 (2), 5 (3) or 8 (4) methyl groups are described.Syntheses of hemins 2 and 3 follow the progression from pyrromethane 12 to t-butyl tripyrrene-carboxylate hydrobromide (17 and 30) and then to a,c-biladiene dihydrobromide (19 and 31), but for reasons of economy in use of labeled monopyrroles, the a,c-biladiene dihydrobromide 40 for hemin 4 is approached in an initially "clockwise" manner by synthesis of a benzyl tripyrrene-carboxylate hydrobromide 37 from the pyrromethane 5.Cyclization of the a,c-biladienes (19, 31, and 40) was accomplished by brief heating in dimethylformamide in the presence of copper(II) chloride.