875210-90-5Relevant articles and documents
Non-Glycosidic and Non-Peptidic Select Inhibitors, and the Use Thereof
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, (2008/06/13)
A new class of non-glycosidic and non-peptidic inhibitors of selectins with low molecular weight according to the general formula 1 is described, as well as methods for their production. These compounds represent a new class of non-toxic, in vivo anti-inf
A novel class of potent nonglycosidic and nonpeptidic pan-selectin inhibitors
Ulbrich, Holger K.,Luxenburger, Andreas,Prech, Philip,Eriksson, Einar E.,Soehnlein, Oliver,Rotzius, Pierre,Lindbom, Lennart,Dannhardt, Gerd
, p. 5988 - 5999 (2007/10/03)
An early step of the inflammatory response, the rolling of leukocytes on activated endothelial cells, is mediated by selectin/carbohydrate interactions. The tetrasaccharide sialy LewisX is a ligand for E-, P-, and L-selectin and therefore serve