875305-86-5 Usage
General Description
7-Bromo-5-chloro-1H-indazole is a chemical compound with the molecular formula C7H4BrClN2 and a molecular weight of 212.48 g/mol. It is a heterocyclic compound containing both bromine and chlorine atoms. This chemical is commonly used in research and pharmaceutical applications, specifically for the synthesis of pharmaceutical drugs and in the development of agrochemicals. It is known to possess various biological activities and can act as a potential building block in the synthesis of new compounds for drug discovery. 7-Bromo-5-chloro-1H-indazole is typically stored and handled in accordance with standard laboratory procedures for handling potentially hazardous chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 875305-86-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,5,3,0 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 875305-86:
(8*8)+(7*7)+(6*5)+(5*3)+(4*0)+(3*5)+(2*8)+(1*6)=195
195 % 10 = 5
So 875305-86-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H4BrClN2/c8-6-2-5(9)1-4-3-10-11-7(4)6/h1-3H,(H,10,11)
875305-86-5Relevant articles and documents
Synthesis, antifungal activity and qsar of novel pyrazole amides as succinate dehydrogenase inhibitors
Du, Shijie,Li, Zhonghao,Tian, Zaimin,Xu, Lu
, p. 74 - 85 (2018/01/26)
We design and synthesize a series of novel pyrazole amides based on the commercialized fungicides and our previous work. The antifungal activity was tested in vitro by mycelial growth inhibition assay. The results show that all the compounds are of antifungal activities against the tested fungi at different levels. Among them, N-(2-(7-bromo-5-chloro-1H-indazol-1-yl)phenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide (Vk) exhibited higher antifungal activity than boscalid against two fungi. Molecular docking study revealed that the carbonyl oxygen atom of Vk forms two hydrogen bonds toward the hydroxyl hydrogens of TYR58 and TRP173.
