87572-41-6

Basic information

• Product Name: C₆₂H₈₃N₁₃O₁₂S
• CAS NO: 87572-41-6
• Molecular Weight: 1234.49
• Mol File: 87572-41-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₆₂H₈₃N₁₃O₁₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₆₂H₈₃N₁₃O₁₂S(87572-41-6)
• EPA Substance Registry System: C₆₂H₈₃N₁₃O₁₂S(87572-41-6)

Safety Data

• Hazardous Substances Data: 87572-41-6(Hazardous Substances Data)

Upstream product

• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 5241-64-5 Boc-D-Trp-OH 

Downstream Products

• 81039-85-2 H-D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Met-NH₂ 

Relevant articles and documents

Synthesis and Biological Activities of Substance P Antagonists

Several substance P analogues containing various D-amino acid modifications have been synthesized by the solid-phase procedure, detached from the solid support by ammonolysis, and purified by gel filtration combined with reversed-phase chromatography.Three compounds were fair to very potent competitive antagonists of substance P on three bioassays, i.e., guinea pig ileum, rabbit mesenteric vein, and guinea pig trachea. 6,D-Trp10>SP(6,11) is a reasonable antagonist in all three bioassays and 4,D-Trp7,9>SP(4-11) is a very potent competitive antagonist with pA2 values ranging around 6.0.