876048-15-6

Basic information

• Product Name: 2-[1-(4-methylphenylsulphonyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yliden] malononitrile
• Synonyms: 2-[1-(4-methylphenylsulphonyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yliden] malononitrile
• CAS NO: 876048-15-6
• Molecular Weight: 363.44
• Mol File: 876048-15-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[1-(4-methylphenylsulphonyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yliden] malononitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[1-(4-methylphenylsulphonyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yliden] malononitrile(876048-15-6)
• EPA Substance Registry System: 2-[1-(4-methylphenylsulphonyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yliden] malononitrile(876048-15-6)

Safety Data

• Hazardous Substances Data: 876048-15-6(Hazardous Substances Data)

Upstream product

• 24310-36-9 1-tosyl-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one 
• 109-77-3 malononitrile 

Downstream Products

• 876048-29-2 2-(5-(4-methylphenylsulphonyl)-6,7-dihydro-5H-benzo[b]pyrimido[5',4':4,5]thieno[3,2-d]azepin-12-ylamino)-1-ethanol 
• 876048-21-4 5-(4-methylphenylsulphonyl)-6,7,11,12-tetrahydro-5H-benzo[b]pyrimido[5',4':4,5]thieno[3,2-d]azepin-12-one 
• 876048-25-8 12-chloro-5-(4-methylphenylsulphonyl)-6,7-dihydro-5H-benzo[b]pyrimido[5',4':4,5]thieno[3,2-d]azepine 
• 876048-17-8 2-amino-6-(4-methylphenylsulphonyl)-5,6-dihydro-4H-benzo[b]thieno[3,2-d]azepin-1-yl cyanide 

Relevant articles and documents

Polyheterocyclic systems: Synthesis and biological activity of novel heterocyclic annelated compounds from 2,3,4,5-tetrahydro-1-benzazepin-5-one

2-Amino-6-(4-methylphenylsulphonyl)-5,6-dihydro-4H-benzo[b]thieno[3,2-d] azepin-1-yl cyanide 3 is subjected to a variety of annelation reactions to give compounds 4-8. Compound 8 when subjected to nucleophilic displacement reactions with different amines affords 12-substituted derivatives 12-15.