87616-84-0

Basic information

• Product Name: Growth hormone releasing peptide
• Synonyms: D-TRP7,ALA8,D-PHE10]-A-MELANOCYTESTIMULATINGHORMONEAMIDEFRAGMENT6-11;(2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(3H-imidazol-4-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]hexanamide;Growth hormone releasing peptide;alpha-melanotropin, fragment 6-11, [D-Trp7,Ala8,D-Phe10];Growth hormone-releasing peptide【synthetic】;L-His-D-Trp-L-Ala-L-Trp-D-Phe-L-Lys-NH2;[His1, Lys6] - GHRP, GHRP- 6;(D-Trp7,Ala8,D-Phe10)-a-MSH (6-11) aMide
• CAS NO: 87616-84-0
• Molecular Formula: C46H56N12O6
• Molecular Weight: 873.01
• Product Categories: Peptide
• Mol File: 87616-84-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1407 °C at 760 mmHg
• Flash Point: 804.7 °C
• Appearance: /
• Density: 1.333 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.664
• Storage Temp.: −20°C
• Solubility: Methanol (Slightly), Water (Slightly)
• PKA: 13.42±0.46(Predicted)
• CAS DataBase Reference: Growth hormone releasing peptide(CAS DataBase Reference)
• NIST Chemistry Reference: Growth hormone releasing peptide(87616-84-0)
• EPA Substance Registry System: Growth hormone releasing peptide(87616-84-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 87616-84-0(Hazardous Substances Data)

Usage

Description

Growth hormone-releasing peptides (GHRPs) are synthetic, non-natural peptides endowed with potent stimulatory effects on somatotrope secretion in animals and humans. They have no structural homology with GHRH and act via specific receptors present either at the pituitary or the hypothalamic level both in animals and in humans.

Uses

Different sources of media describe the Uses of 87616-84-0 differently. You can refer to the following data:
1. Growth hormone releasing peptide-6 can promote the secretion of growth hormone, regulate food intake, increase weight, and promote animal growth.
2. L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide is a growth hormone releasing peptide.

Mechanism of action

Growth hormone releasing peptide is generally accepted that GHRPs stimulate the release of GH by acting at the level of the pituitary through a receptor different to that for the endogenous GH-releasing hormone (GHRH). In addition, it has been reported that there are specific binding sites for these peptides in the hypothalamus and that systemic administration of GHRPs increases the expression of the immediate early gene c-fos in a subpopulation of hypothalamic neurons.

InChI:InChI=1/C46H56N12O6/c1-27(54-44(62)39(20-29-23-51-35-15-7-5-13-32(29)35)57-43(61)34(48)22-31-25-50-26-53-31)42(60)56-40(21-30-24-52-36-16-8-6-14-33(30)36)46(64)58-38(19-28-11-3-2-4-12-28)45(63)55-37(41(49)59)17-9-10-18-47/h2-8,11-16,23-27,34,37-40,51-52H,9-10,17-22,47-48H2,1H3,(H2,49,59)(H,50,53)(H,54,62)(H,55,63)(H,56,60)(H,57,61)(H,58,64)/t27-,34-,37-,38?,39+,40-/m0/s1