877133-58-9

Basic information

• Product Name: 3-PYRIDINOL, 6-CHLORO-4-IODO-
• Synonyms: 3-PYRIDINOL, 6-CHLORO-4-IODO-;6-chloro-4-iodo-3-hydroxypyridine;6-chloro-4-iodopyridin-3-ol;2-Chloro-5-hydroxy-4-iodopyridine;6-Chloro-4-Iodopyridin-3-Ol(WXC03698)
• CAS NO: 877133-58-9
• Molecular Formula: C₅H₃ClINO
• Molecular Weight: 255.438
• Mol File: 877133-58-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 332.821 °C at 760 mmHg
• Flash Point: 155.085 °C
• Appearance: /
• Density: 2.219 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.691
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 6.41±0.10(Predicted)
• CAS DataBase Reference: 3-PYRIDINOL, 6-CHLORO-4-IODO-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PYRIDINOL, 6-CHLORO-4-IODO-(877133-58-9)
• EPA Substance Registry System: 3-PYRIDINOL, 6-CHLORO-4-IODO-(877133-58-9)

Safety Data

• Hazardous Substances Data: 877133-58-9(Hazardous Substances Data)

Usage

General Description

3-PYRIDINOL, 6-CHLORO-4-IODO- is a chemical compound with the molecular formula C5H3ClIN2O. It is a derivative of pyridine and contains both chlorine and iodine atoms. This chemical is commonly used in the synthesis of pharmaceuticals and agrochemicals. It has shown potential as an intermediate in the production of various compounds with biological activities. Additionally, it is also used as a building block in organic synthesis for the preparation of different functionalized molecules for various applications. Overall, 3-PYRIDINOL, 6-CHLORO-4-IODO- has a wide range of potential uses in the chemical and pharmaceutical industries.

InChI:InChI=1/C5H3ClINO/c6-5-1-3(7)4(9)2-8-5/h1-2,9H

Upstream product

• 877133-57-8 2-chloro-4-iodo-5-(methoxymethoxy)pyridine 
• 877133-56-7 2-chloro-5-(methoxymethoxy)pyridine 
• 41288-96-4 6-chloropyridine-3-ol 

Downstream Products

• 1441754-60-4 5-(2-chloro-5-methoxy-pyridin-4-yl)-4-(4-chloro-2-methyl-phenyl)-3-isopropyl-2-(2-methoxy-phenyl)-4,5-dihydro-2H-pyrrolo[3,4-c]pyrazol-6-one 
• 1211516-07-2 2-chloro-4-iodo-5-methoxy-pyridine 
• 1451163-47-5 4-[5-(2-fluoro-4-methanesulfonyl-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid 1-methyl-cyclopropyl ester 
• 1451163-46-4 4-[5-(2-fluoro-4-methanesulfonyl-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid isopropyl ester 
• 1451163-45-3 5-(2-fluoro-4-methanesulfonyl-phenyl)-2-[1-(2-fluoro-2-methyl-propyl)-piperidin-4-yl]-furo[2,3-c]pyridine 
• 1451163-44-2 5-(2-fluoro-4-methanesulfonyl-phenyl)-2-[1-(1-trifluoromethyl-cyclopropylmethyl)-piperidin-4-yl]-furo[2,3-c]pyridine 
• 1451163-43-1 2-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-5-(2-fluoro-4-methanesulfonyl-phenyl)-furo[2,3-c]pyridine 
• 1451163-39-5 4-[5-(4-methanesulfonylmethyl-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1451163-36-2 4-[5-(4-benzyloxycarbonyl-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1451163-33-9 4-[5-(4-ethylcarbamoyl-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1451163-32-8 4-[5-(4-cyano-3-fluoro-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1382136-84-6 4-[5-(2-fluoro-4-methanesulfonyl-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1451163-59-9 1-{4-[5-(2-fluoro-4-methanesulfonyl-phenyl)-furo[2,3-c]pyridin-2-yl]-piperidin-1-yl}-2-methyl-propan-2-ol 
• 1451163-58-8 5-(2-fluoro-4-methanesulfonyl-phenyl)-2-piperidin-4-yl-furo[2,3-c]pyridine 

Relevant articles and documents

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The invention is concerned with the compounds of formula I and salts thereof and other compounds of formulas II-IX as disclosed herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formulas I-IX as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain or asthma.

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