877149-10-5Relevant articles and documents
CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF
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Paragraph 0297-0300, (2020/12/25)
A cyclic amine derivative represented by general Formula (I): wherein R1 represents an alkyl group having 1 to 3 carbon atoms; A represents a group represented by general Formula (II-1), (II-2), or (II-3): R2 represents a hydrogen at
PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS
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Page/Page column 118, (2018/12/13)
The present invention relates to phenyl derivatives of formula (I) Formula (I) wherein (R1)n, R3, R4a, R4b, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (III) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.
ISOINDOLONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS
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Page/Page column 60, (2008/06/13)
The present invention is directed to compounds of formula (I), wherein R1 is a ring and n is a number from 1 to 8. The invention also relates to use of the compounds in therapy as metabotropic glutamate receptor modulators, particularly in neurological and psychiatric disorders.