877160-63-9

Basic information

• Product Name: 4-Amino-2-chlorophenylboronic acid, pinacol ester
• Synonyms: 4-Amino-2-chlorophenylboronic acid, pinacol ester;[3-Chloro-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]aMine;3-Chloro-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)aniline
• CAS NO: 877160-63-9
• Molecular Formula: C₁₂H₁₇BClNO₂
• Molecular Weight: 253.53
• Mol File: 877160-63-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 374.5°C at 760 mmHg
• Flash Point: 180.3°C
• Appearance: /
• Density: 1.15g/cm³
• Vapor Pressure: 8.3E-06mmHg at 25°C
• Refractive Index: 1.53
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 3.17±0.10(Predicted)
• CAS DataBase Reference: 4-Amino-2-chlorophenylboronic acid, pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-2-chlorophenylboronic acid, pinacol ester(877160-63-9)
• EPA Substance Registry System: 4-Amino-2-chlorophenylboronic acid, pinacol ester(877160-63-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 877160-63-9(Hazardous Substances Data)

Usage

General Description

4-Amino-2-chlorophenylboronic acid, pinacol ester is a chemical compound consisting of a boronic acid group, an amino group, and a chlorine atom attached to a phenyl ring. The pinacol ester group is attached to the boronic acid, making it a stable and easy-to-handle form of the compound. This chemical is often used in organic synthesis as a building block for pharmaceuticals, agrochemicals, and materials science. It is a versatile reagent in Suzuki-Miyaura cross-coupling reactions, allowing for the formation of carbon-carbon bonds between aryl and heteroaryl compounds. The pinacol ester moiety also provides protection for the boronic acid functionality, making it more stable and easier to handle in various chemical reactions.

InChI:InChI=1/C12H17BClNO2/c1-11(2)12(3,4)17-13(16-11)9-6-5-8(15)7-10(9)14/h5-7H,15H2,1-4H3

Upstream product

• 21402-26-6 4-bromo-3-chloroaniline 
• 73183-34-3 bis(pinacol)diborane 
• 121-87-9 2-Chloro-4-nitroaniline 
• 1426804-80-9 2-(2-chloro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

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