878436-47-6 Usage
Description
2-(4-fluorophenyl)imidazo[1,2-a]pyrimidine-3-carbaldehyde, also known as FIPI-3, is a chemical compound with potential pharmaceutical applications. It is a fluorescent probe that can be used to study lipid signaling pathways, specifically the role of phosphatidylinositol-4,5-bisphosphate in cellular functions. FIPI-3 has been shown to inhibit PI(4,5)P2-regulated processes, making it a valuable tool for researching lipid signaling and potential therapeutic targets.
Uses
Used in Pharmaceutical Research:
2-(4-fluorophenyl)imidazo[1,2-a]pyrimidine-3-carbaldehyde is used as a fluorescent probe for studying lipid signaling pathways and the role of phosphatidylinositol-4,5-bisphosphate in cellular functions. It is particularly useful for investigating PI(4,5)P2-regulated processes, which can help identify potential therapeutic targets.
Used in Anti-cancer Applications:
2-(4-fluorophenyl)imidazo[1,2-a]pyrimidine-3-carbaldehyde is used as a potential anti-cancer agent due to its ability to inhibit PI(4,5)P2-regulated processes. This property makes it a promising candidate for the development of new pharmaceutical drugs that target cancer cells.
Used in Anti-inflammatory Applications:
2-(4-fluorophenyl)imidazo[1,2-a]pyrimidine-3-carbaldehyde is used as a potential anti-inflammatory agent, as its ability to inhibit PI(4,5)P2-regulated processes may also have implications for modulating inflammatory responses in the body. This makes it a candidate for the development of new drugs to treat inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 878436-47-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,8,4,3 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 878436-47:
(8*8)+(7*7)+(6*8)+(5*4)+(4*3)+(3*6)+(2*4)+(1*7)=226
226 % 10 = 6
So 878436-47-6 is a valid CAS Registry Number.
878436-47-6Relevant articles and documents
Design, synthesis and biological evaluation of imidazopyridine/imidazopyrimidine-benzimidazole conjugates as potential anticancer agents
Kamal, Ahmed,Bharath Kumar,Lakshma Nayak,Reddy, Vangala Santhosh,Shaik, Anver Basha,Rajender,Kashi Reddy
, p. 606 - 612 (2015)
A series of imidazopyridine/imidazopyrimidine-benzimidazole conjugates (11a-t) were synthesized and evaluated for their antiproliferative activity. All of these conjugates showed moderate to improved cytotoxic activity against the human cervical (Hela), l
