879486-21-2

Basic information

• Product Name: [4-(1'-Amino-4'-methylpiperazine-1-carbonyl)-phenyl] boronic acid pinacol ester
• Synonyms: [4-(1'-Amino-4'-methylpiperazine-1-carbonyl)-phenyl] boronic acid pinacol ester
• CAS NO: 879486-21-2
• Molecular Formula: C18H28BN3O3
• Molecular Weight: 345.24422
• Mol File: 879486-21-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.14±0.1 g/cm3(Predicted)
• PKA: 12.25±0.20(Predicted)
• CAS DataBase Reference: [4-(1'-Amino-4'-methylpiperazine-1-carbonyl)-phenyl] boronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(1'-Amino-4'-methylpiperazine-1-carbonyl)-phenyl] boronic acid pinacol ester(879486-21-2)
• EPA Substance Registry System: [4-(1'-Amino-4'-methylpiperazine-1-carbonyl)-phenyl] boronic acid pinacol ester(879486-21-2)

Safety Data

• Hazardous Substances Data: 879486-21-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
[4-(1'-Amino-4'-methylpiperazine-1-carbonyl)-phenyl] boronic acid pinacol ester is used as a reagent in the Suzuki-Miyaura cross-coupling reaction for forming carbon-carbon bonds. This reaction is a widely employed method in organic synthesis, allowing for the creation of complex molecular structures.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, [4-(1'-Amino-4'-methylpiperazine-1-carbonyl)-phenyl] boronic acid pinacol ester is used as a tool for drug discovery. Its ability to selectively bind to and inhibit specific enzymes makes it a promising candidate for the development of new therapeutic agents.
Used in Carbohydrate Chemistry:
[4-(1'-Amino-4'-methylpiperazine-1-carbonyl)-phenyl] boronic acid pinacol ester is used in carbohydrate chemistry due to its capacity to form stable complexes with diols. This property allows it to be employed in the study and manipulation of carbohydrates, which are essential components of many biological systems.
Used as a Sensor for Detecting Sugars:
The boronic acid functionality of [4-(1'-Amino-4'-methylpiperazine-1-carbonyl)-phenyl] boronic acid pinacol ester also enables it to be used as a sensor for detecting sugars. This application can be particularly useful in the fields of diagnostics, food science, and biochemistry, where accurate sugar detection is crucial.
Overall, [4-(1'-Amino-4'-methylpiperazine-1-carbonyl)-phenyl] boronic acid pinacol ester is a versatile and valuable compound with a wide range of applications across various industries, including organic synthesis, medicinal chemistry, carbohydrate chemistry, and as a sensor for detecting sugars.

Relevant articles and documents

SUBSTITUTED BIPHENYL DERIVATIVE

The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: wherein R1 represents a C6-C10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C1-C6 alkyl)amino group, a di-(C1-C6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C1-C6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R3 represents a C1-C6 alkyl group, and so on; and R4 represents a C1-C6 alkyl group, and so on.