87974-77-4

Basic information

• Product Name: L-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
• Synonyms: L-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
• CAS NO: 87974-77-4
• Molecular Formula: C₁₂H₂₃NO₄
• Molecular Weight: 245
• Mol File: 87974-77-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 327.8±25.0 °C(Predicted)
• Appearance: /
• Density: 1.010±0.06 g/cm3(Predicted)
• PKA: 11.21±0.46(Predicted)
• CAS DataBase Reference: L-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester(87974-77-4)
• EPA Substance Registry System: L-Norleucine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester(87974-77-4)

Safety Data

• Hazardous Substances Data: 87974-77-4(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 6404-28-0 Boc-Nle-OH 
• 811-49-4 ethyllithium 
• 76969-87-4 tert-Butyloxycarbonyl-L-α-amino-γ-bromobutyric acid methyl ester 
• 335628-17-6 (4S,5R)-3-tert-butoxycarbonyl-4-butyl-5-methoxy-2-oxazolidinone 
• 93267-04-0 N-(tert-butoxycarbonyl)-L-3-iodoalanine methyl ester 
• 2417-93-8 propyllithium 
• 56926-94-4 methyl (2S)-2-[N-(t-butoxycarbonyl)amino]-3-(4-methylbenzenesulfonyl)-oxypropionate 
• 76969-87-4 methyl (2S)-4-bromo-2-[(tert-butoxycarbonyl)amino]butanoate 
• 101650-17-3 (S)-2-amino-4-bromobutyric acid methyl ester 
• 110579-52-7 (E)-(S)-2-tert-Butoxycarbonylamino-6-hydroxy-hex-4-enoic acid methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 3844-54-0 HCl-L-norleucine methyl ester 
• 335627-74-2 (4S,5R)-4-butyl-5-methoxy-2-oxazolidinone 

Downstream Products

• 104062-70-6 (S)-N-Boc-leucinal 
• 6404-28-0 Boc-Nle-OH 
• 865537-92-4 2-[(S)-2-(1-Benzyl-propoxycarbonylamino)-1-hydroxy-hexyl]-thiazole-4-carboxylic acid ethyl ester 
• 865537-90-2 2-[(S)-2-(1-Benzyl-2-methyl-propoxycarbonylamino)-1-hydroxy-hexyl]-thiazole-4-carboxylic acid ethyl ester 
• 865537-95-7 2-[(S)-2-(1-Benzyl-3-methyl-butoxycarbonylamino)-1-hydroxy-hexyl]-thiazole-4-carboxylic acid ethyl ester 
• 865537-85-5 2-[(S)-2-((S)-2-Cyclohexyl-1-methyl-ethoxycarbonylamino)-1-hydroxy-hexyl]-thiazole-4-carboxylic acid ethyl ester 
• 865537-89-9 {(S)-1-[Hydroxy-(4-trifluoromethyl-thiazol-2-yl)-methyl]-pentyl}-carbamic acid (S)-2-cyclohexyl-1-methyl-ethyl ester 
• 865537-84-4 2-[(S)-2-((S)-2-Cyclohexyl-1-methyl-ethoxycarbonylamino)-1-hydroxy-hexyl]-4-methyl-thiazole-5-carboxylic acid ethyl ester 
• 116640-17-6 tert-butyl [(1S)-1-(hydroxymethyl)pentyl]carbamate 
• 497947-62-3 {(S)-1-[2-Cyano-2-(triphenyl-λ⁵-phosphanylidene)-acetyl]-pentyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

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Both enantiomers of trans-5-benzyloxy-4-methoxy- (BMOx) and trans-4,5-dimethoxy-2-oxazolidinones (DMOx), which are readily accessible from simple 2-oxazolone heterocycles, represent good candidates for a new class of chiral synthons for use in the preparation of optically pure alpha-amino aldehydes and alpha-amino acids, respectively.

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