880549-34-8

Basic information

• Product Name: 5-bromo-1-(2-chloro-6-fluoro-benzyl)-1H-pyrimidine-2,4-dione
• Synonyms: 5-bromo-1-(2-chloro-6-fluoro-benzyl)-1H-pyrimidine-2,4-dione
• CAS NO: 880549-34-8
• Molecular Weight: 333.544
• Mol File: 880549-34-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-bromo-1-(2-chloro-6-fluoro-benzyl)-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-1-(2-chloro-6-fluoro-benzyl)-1H-pyrimidine-2,4-dione(880549-34-8)
• EPA Substance Registry System: 5-bromo-1-(2-chloro-6-fluoro-benzyl)-1H-pyrimidine-2,4-dione(880549-34-8)

Safety Data

• Hazardous Substances Data: 880549-34-8(Hazardous Substances Data)

Upstream product

• 51-20-7 5-bromouracil 
• 68220-26-8 2-(bromomethyl)-1-chloro-3-fluorobenzene 

Downstream Products

• 880550-55-0 {2-[5-bromo-3-(2-chloro-6-fluoro-benzyl)-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

Uracils as potent antagonists of the human gonadotropin-releasing hormone receptor without atropisomers

Uracil derivatives were designed and synthesized to avoid atropisomers observed in the 6-methyluracils as antagonists of the human GnRH receptor. Optimization at the 1- and 5-positions of the uracil resulted in potent compounds such as 24 (Ki = 0.45 nM).