881683-84-7

Basic information

• Product Name: 8-Nonenoic acid, 2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, (2R)-
• Synonyms: 8-Nonenoic acid, 2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, (2R)-;(R)-N-Boc-2-(6'-heptenyl)glycine;(2R)-2-{[(tert-butoxy)carbonyl]amino}non-8-enoic acid;(R)-2-((tert-butoxycarbonyl)amino)non-8-enoic acid;Boc-(2R)-2-Amino-8-nonenoic acid
• CAS NO: 881683-84-7
• Molecular Formula: C₁₄H₂₅NO₄
• Molecular Weight: 271.3526
• Mol File: 881683-84-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-Nonenoic acid, 2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Nonenoic acid, 2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, (2R)-(881683-84-7)
• EPA Substance Registry System: 8-Nonenoic acid, 2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, (2R)-(881683-84-7)

Safety Data

• Hazardous Substances Data: 881683-84-7(Hazardous Substances Data)

Usage

Description

8-Nonenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2R)is a unique form of nonenoic acid with a 2-[(1,1-dimethylethoxy)carbonyl]amino group attached to the 2nd carbon in a R configuration. 8-Nonenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2R)is known for its specific stereochemistry, which influences its reactivity and biological activity, making it a valuable asset in the pharmaceutical and chemical industries.

Uses

Used in Organic Synthesis:
8-Nonenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2R)is utilized as a key component in organic synthesis, serving as a building block for the creation of various pharmaceuticals and agrochemicals. Its unique structure allows for the development of new compounds with potential therapeutic and agricultural applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 8-Nonenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2R)is used as an intermediate for the synthesis of drugs. Its specific stereochemistry plays a crucial role in the effectiveness and selectivity of the resulting pharmaceuticals, contributing to the development of more targeted and potent medications.
Used in Agrochemical Industry:
8-Nonenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2R)also finds application in the agrochemical industry, where it is used as a precursor for the synthesis of pesticides and other agricultural chemicals. Its unique properties can lead to the creation of more effective and environmentally friendly products.
Used as a Flavoring Agent in Food Products:
In the food industry, 8-Nonenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2R)is used as a flavoring agent, particularly in the production of artificial fruit flavors. Its ability to mimic natural fruit flavors adds value to food products, enhancing their taste and appeal to consumers.

Upstream product

• 881683-81-4 (R)-2-tert-butoxycarbonylamino-8-nonenoic acid ethyl ester 

Downstream Products

• 1009637-40-4 C₃₀H₄₆N₂O₅ 
• 744251-30-7 C₄₁H₅₃N₇O₆ 
• 744251-31-8 C₄₁H₅₃N₇O₆ 
• 744251-06-7 C₃₄H₄₇N₇O₆ 

Relevant articles and documents

Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides

Inhibitors of histone deacetylases (HDACs) are a promising class of anticancer agents that effect gene regulation. To know the interaction of aliphatic cap groups with HDACs, cyclic tetrapeptide and bicyclic peptide disulfide hybrids were synthesized without aromatic ring in their macrocyclic framework. Benzene ring of l-Phe in chlamydocin was replaced with several aliphatic amino acids and also a fused bicyclic tetrapeptide was synthesized by ring closing metathesis using Grubb's first generation catalyst. The inhibitory activities of the cyclic peptides against histone deacetylase enzymes were evaluated, which demonstrated most of them are interesting candidates as anticancer agents.