88190-77-6 Usage
General Description
6-CHLORO-4-PHENYL-3, 4-DIHYDROQUINAZOLINE-2-CARBOXYLIC ACID is a chemical compound with the molecular formula C16H12ClNO2. It is a quinazoline derivative with a chloro and phenyl group attached to the 6 and 4 position, respectively. It also contains a carboxylic acid group at the 2 position. 6-CHLORO-4-PHENYL-3, 4-DIHYDROQUINAZOLINE-2-CARBOXYLIC ACID is often used in medicinal and pharmaceutical research as it exhibits potential biological activities and can be used as a building block in the synthesis of other organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 88190-77-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,1,9 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 88190-77:
(7*8)+(6*8)+(5*1)+(4*9)+(3*0)+(2*7)+(1*7)=166
166 % 10 = 6
So 88190-77-6 is a valid CAS Registry Number.
88190-77-6Relevant articles and documents
Reactions of hydroxyglycines. New synthetic routes to 4-phenylquinazoline derivatives
Hoefnagel,Van Koningsveld,Van Meurs,Peters,Sinnema,Van Bekkum
, p. 6899 - 6912 (2007/10/02)
Reaction of hydroxyglycine with 2-aminobenzophenones gives 1,2-dihydro-4-phenyl-quinazoline-2-carboxylic acids in high yields and under mild conditions. These can be smoothly converted into the corresponding 3,4-dihydro isomers and into quinazoline derivatives via rearrangement and oxidation by air, respectively. The X-ray crystallographic structure of 6-chloro-1,2-dihydro-1-methyl-4-phenylquinazoline-2-carboxylic acid shows the carboxylate group at C(2) and the methyl group at N(1) to be in axial positions.
