88494-66-0Relevant articles and documents
Efficient Catalytic Asymmetric Alkylations. 3. A Kinetic and Mechanistic Study of the Enantioselective Phase-Transfer Methylation of 6,7-Dichloro-5-methoxy-2-phenyl-1-indanone
Hughes, D. L.,Dolling, U.-H.,Ryan, K. M.,Schoenewaldt, E. F.,Grabowski, E. J. J.
, p. 4745 - 4752 (2007/10/02)
The phase-transfer methylation of 6,7-dichloro-5-methoxy-2-phenyl-1-indanone by MeCl in 50percent NaOH/toluene using substituted N-benzylcinchoninium halides has provided the methylated indanone 2 in ee's up to 94percent.The effects of solvent, alkylating