885043-39-0Relevant articles and documents
Detrifluoroacetylation Reaction of Trifluoromethyl-β-diketones: Facile Method for the Synthesis of Succinimide Derivatives and 1,4-Diketones
Wang, Li-Hua,Zhao, Jing
, p. 4345 - 4348 (2018)
Currently, a great deal of research efforts are focused on C–C bond activation for development of novel synthetic methodology. In this paper, a detrifluoroacetylation of trifluoromethyl-β-diketones is described, which allows for the synthesis of succinimides and 1,4-diketones through cascade Michael addition/retro-Claisen reaction and nucleophilic substitution/retro-Claisen reaction. The readily available trifluoromethyl-β-diketones, wide substrate scope, and mild conditions make this method very practical.
Copper-Catalyzed Three-Component Reactions of 2-Iodo-2,2-difluoroacetophenones, Alkynes, and Trimethylsilyl Cyanide
Wu, Pingjie,Zheng, Cheng,Wang, Xia,Wu, Jingjing,Wu, Fanhong
supporting information, p. 1420 - 1423 (2021/02/01)
A Cu(I)-catalyzed three-component reaction of 2-iodo-2,2-difluoroacetophenones, alkynes, and TMSCN is described. The reaction provided a facile method for the synthesis of difluoroacyl-substituted nitriles, which might be served as potentially useful fluo