88580-27-2

Basic information

• Product Name: desacetylravidomycin
• Synonyms: desacetylravidomycin;4-[3-(Dimethylamino)-3,6-dideoxy-α-D-altropyranosyl]-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one;Antibiotic AY-26623;AY-26623;Deacetylravidomycin;WK-6326-M7;O-Deacetylravidomycin
• CAS NO: 88580-27-2
• Molecular Formula: C29H31NO8
• Molecular Weight: 521.563
• Mol File: 88580-27-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 792°C at 760 mmHg
• Flash Point: 432.8°C
• Appearance: /
• Density: 1.4g/cm³
• Vapor Pressure: 1.94E-26mmHg at 25°C
• Refractive Index: 1.679
• CAS DataBase Reference: desacetylravidomycin(CAS DataBase Reference)
• NIST Chemistry Reference: desacetylravidomycin(88580-27-2)
• EPA Substance Registry System: desacetylravidomycin(88580-27-2)

Safety Data

• Hazardous Substances Data: 88580-27-2(Hazardous Substances Data)

Usage

Description

Desacetylravidomycin is a more active and stable analogue of the ravidomycin complex, which is produced by Streptomyces ravidus. It exhibits potent, light-dependent antitumor activity and is considered a promising pharmaceutical candidate due to its ability to act as a topoisomerase II inhibitor.

Uses

Used in Anticancer Applications:
Desacetylravidomycin is used as an anticancer agent for its potent, light-dependent antitumor activity. It is particularly effective against various types of cancer due to its ability to inhibit topoisomerase II, a crucial enzyme involved in DNA replication and transcription.
Used in Pharmaceutical Industry:
Desacetylravidomycin is used as a pharmaceutical agent for its potential applications in cancer treatment. Its light-dependent antitumor activity and topoisomerase II inhibitory properties make it a valuable compound for the development of novel cancer therapies.

InChI:InChI=1/C29H31NO8/c1-7-14-10-17-21(19(11-14)35-5)16-12-20(36-6)23-18(31)9-8-15(22(23)27(16)38-29(17)34)28-26(33)24(30(3)4)25(32)13(2)37-28/h7-13,24-26,28,31-33H,1H2,2-6H3/t13-,24-,25-,26+,28-/m1/s1