886365-88-4

Basic information

• Product Name: (5-BROMO-PYRIMIDIN-2-YL)-PHENYL-AMINE
• Synonyms: (5-BROMO-PYRIMIDIN-2-YL)-PHENYL-AMINE;5-BROMO-N-PHENYLPYRIMIDIN-2-AMINE;5-Bromo-2-phenylaminopyrimidine
• CAS NO: 886365-88-4
• Molecular Formula: C₁₀H₈BrN₃
• Molecular Weight: 250.09
• Mol File: 886365-88-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: (5-BROMO-PYRIMIDIN-2-YL)-PHENYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (5-BROMO-PYRIMIDIN-2-YL)-PHENYL-AMINE(886365-88-4)
• EPA Substance Registry System: (5-BROMO-PYRIMIDIN-2-YL)-PHENYL-AMINE(886365-88-4)

Safety Data

• Hazardous Substances Data: 886365-88-4(Hazardous Substances Data)

Usage

General Description

The chemical compound "(5-Bromo-pyrimidin-2-yl)-phenyl-amine" is a derivative of pyrimidine and aniline with the chemical formula C11H9BrN4. It is a heterocyclic organic compound with a bromine atom attached to the pyrimidine ring and a phenylamine group attached to the 2-position of the ring. (5-BROMO-PYRIMIDIN-2-YL)-PHENYL-AMINE has potential applications in pharmaceutical and agrochemical industries due to its unique structure and properties. It may be used as a building block in the synthesis of various biologically active compounds and materials. Additionally, it can serve as a valuable intermediate in the production of pharmaceuticals and other fine chemicals. Further research and development of this compound may lead to the discovery of new therapeutic agents and agrochemicals.

Upstream product

• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 62-53-3 aniline 

Downstream Products

• 956128-05-5 2-(phenylamino)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyrimidine 
• 890021-35-9 2-fluoro-4-(2-(phenylamino)pyrimidin-5-yl)phenol 
• 1080028-75-6 2-(phenylamino)pyrimidine-5-carbaldehyde 
• 1257628-66-2 4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(2-(2-(phenylamino)pyrimidin-5-yl)ethynyl)benzamide 
• 101987-05-7 phenyl-(5-phenyl-pyrimidin-2-yl)-amine 
• 1644540-73-7 3-phenylbenzo[4,5]imidazo[1,2-a]pyrimidine 
• 937796-09-3 C₁₂H₁₁N₃O₂ 
• 450368-25-9 C₁₁H₉N₃O₂ 
• 1581701-32-7 N-(2-methyl-5-((4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)phenyl)-2-(phenylamino)pyrimidine-5-carboxamide 
• 1402816-41-4 1-acetyl-3-(5-bromo-pyrimidin-2-yl)-1-tert-butyl-3-phenyl-urea 
• 960300-09-8 5-(4-(benzyloxy)-3-fluorophenyl)-N-phenylpyrimidin-2-amine 

Relevant articles and documents

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds of Formula (I) or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, wherein A, J, R1, R2, R3, R4, R5, R6, R7, R9, X, m and n are as described herein, compositions thereof, and methods and uses thereof.

A copper-mediated tandem reaction through isocyanide insertion into N-H bonds: Efficient access to unsymmetrical tetrasubstituted ureas

A copper-mediated multi-component reaction was developed through isocyanide insertion into N-H bonds of less active secondary arylamines. This approach leads to an efficient synthesis of unsymmetrical tetrasubstituted ureas in one pot. The Royal Society of Chemistry.

QUINOLINE COMPOUNDS AND METHODS OF USE

Compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof, are useful for inhibiting receptor tyrosine kinases and for treating hyperproliferative disorders mediated thereby. Methods of using compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. [ Formula I]