886368-65-6

Basic information

• Product Name: 2-(4-TRIFLUOROMETHOXY-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID
• Synonyms: 2-(4-TRIFLUOROMETHOXY-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID;2-(4-Trifluoromethoxy-Phenyl)-Thiazole-4-Carboxylic Acid(WX614127)
• CAS NO: 886368-65-6
• Molecular Formula: C₁₁H₆F₃NO₃S
• Molecular Weight: 289.2304496
• Mol File: 886368-65-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-TRIFLUOROMETHOXY-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-TRIFLUOROMETHOXY-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID(886368-65-6)
• EPA Substance Registry System: 2-(4-TRIFLUOROMETHOXY-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID(886368-65-6)

Safety Data

• Hazardous Substances Data: 886368-65-6(Hazardous Substances Data)

Usage

General Description

The chemical 2-(4-trifluoromethoxy-phenyl)-thiazole-4-carboxylic acid is a compound with a thiazole ring and a carboxylic acid functional group. It is a thiazole derivative that contains a phenyl group with a trifluoromethoxy substituent. 2-(4-TRIFLUOROMETHOXY-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID is used in the synthesis of various pharmaceuticals and agrochemicals due to its potential biological activities. It may have applications in the development of new drugs and also in the field of crop protection. Its unique structure makes it suitable for various chemical reactions and potential therapeutic uses.

Upstream product

• 886368-15-6 ethyl 2-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-4-carboxylate 

Downstream Products

• 1258268-78-8 C₁₉H₁₅F₃N₂O₂S 

Relevant articles and documents

Subtype-selective Nav1.8 sodium channel blockers: Identification of potent, orally active nicotinamide derivatives

A series of aryl-substituted nicotinamide derivatives with selective inhibitory activity against the Nav1.8 sodium channel is reported. Replacement of the furan nucleus and homologation of the anilide linker in subtype-selective blocker A-803467 (1) provided potent, selective derivatives with improved aqueous solubility and oral bioavailability. Representative compounds from this series displayed efficacy in rat models of inflammatory and neuropathic pain.