886497-77-4 Usage
Description
3-Fluoro-5-methylbenzoyl chloride is an organic compound characterized by the presence of a fluorine atom at the 3-position and a methyl group at the 5-position on a benzene ring. It features a benzoyl chloride functional group, which is a derivative of benzoic acid with a chlorine atom attached to the carbonyl group. 3-FLUORO-5-METHYLBENZOYL CHLORIDE is known for its reactivity and is commonly used as a building block in the synthesis of various organic molecules.
Uses
Used in Pharmaceutical Industry:
3-Fluoro-5-methylbenzoyl chloride is used as a reactant for the synthesis of substituted pyrido-pyrimidines, which are potent mGlu5 receptor antagonists. These antagonists have potential applications in the treatment of neurological disorders and cognitive impairments, such as schizophrenia, Alzheimer's disease, and Fragile X syndrome.
In the synthesis process, 3-fluoro-5-methylbenzoyl chloride serves as a key intermediate, providing the necessary structural features to form the desired pyrido-pyrimidine scaffold. The introduction of the fluorine and methyl substituents on the benzene ring can modulate the biological activity and selectivity of the resulting compounds, making them more effective in targeting the mGlu5 receptor.
Overall, 3-fluoro-5-methylbenzoyl chloride plays a crucial role in the development of novel therapeutic agents with potential applications in the treatment of various neurological conditions. Its unique structural features and reactivity make it a valuable building block in the design and synthesis of new drugs targeting the mGlu5 receptor.
Check Digit Verification of cas no
The CAS Registry Mumber 886497-77-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,4,9 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 886497-77:
(8*8)+(7*8)+(6*6)+(5*4)+(4*9)+(3*7)+(2*7)+(1*7)=254
254 % 10 = 4
So 886497-77-4 is a valid CAS Registry Number.
