886990-82-5

Basic information

• Product Name: C₃₄H₅₀N₂O₃SSi
• Synonyms: C₃₄H₅₀N₂O₃SSi
• CAS NO: 886990-82-5
• Molecular Weight: 594.934
• Mol File: 886990-82-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₄H₅₀N₂O₃SSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₄H₅₀N₂O₃SSi(886990-82-5)
• EPA Substance Registry System: C₃₄H₅₀N₂O₃SSi(886990-82-5)

Safety Data

• Hazardous Substances Data: 886990-82-5(Hazardous Substances Data)

Upstream product

• 143262-21-9 indoline-7-carboxyaldehyde 
• 1074-87-9 indole-7-methanol 
• 1074-88-0 1H-indole-7-carbaldehyde 

Downstream Products

• 886993-17-5 C₃₄H₅₀N₂O₃SSi 

Relevant articles and documents

Asymmetric synthesis of highly substituted azapolycyclic compounds via 2-alkenyl sulfoximines: Potential scaffolds for peptide mimetics

The application of metalated, enantiomerically pure acyclic and cyclic 2-alkenyl sulfoximines for the synthesis of highly substituted aza(poly)cyclic ring systems is described. The method relies on a one-pot combination of a reagent-controlled allyl transfer reaction to α- or β-amino aldehydes, followed by a Michael-type cyclization of the intermediate vinyl sulfoximines generated in the first step. The sulfur-free target compounds are preferentially obtained by samarium iodide treatment of the sulfonimidoyl substituted heterocycles. In addition to this methodological work, initial results on the biological activity of selected examples are reported. Furthermore, a concept for the transformation of peptidic lead structures into non-peptide mimetics is described, and the relevance of the new approach to highly substituted azaheterocycles in this context is discussed.