887266-98-0Relevant articles and documents
Design, synthesis and biological evaluation of novel benzothiadiazine derivatives as potent PI3Kδ-selective inhibitors for treating B-cell-mediated malignancies
Ma, Xiaodong,Wei, Jun,Wang, Chang,Gu, Dongyan,Hu, Yongzhou,Sheng, Rong
, p. 112 - 125 (2019/03/17)
A series of 24 benzothiadiazine derivatives with structural novelty were designed, synthesized and biologically evaluated as PI3Kδ-selective inhibitors. As a consequence of the structure-activity relationship (SAR) study, compounds 63 and 71 were identifi