887267-38-1

Basic information

• Product Name: 3-CHLORO-2,4-DIFLUOROBENZONITRILE
• Synonyms: 3-Chloro-2,4-difluorobenzonitrile;Benzonitrile, 3-chloro-2,4-difluoro-
• CAS NO: 887267-38-1
• Molecular Formula: C₇H₂ClF₂N
• Molecular Weight: 173.55
• Mol File: 887267-38-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 208.8ºC at 760 mmHg
• Flash Point: 80.1ºC
• Appearance: /
• Density: 1.43g/cm3
• Vapor Pressure: 0.21mmHg at 25°C
• Refractive Index: 1.513
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-CHLORO-2,4-DIFLUOROBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-2,4-DIFLUOROBENZONITRILE(887267-38-1)
• EPA Substance Registry System: 3-CHLORO-2,4-DIFLUOROBENZONITRILE(887267-38-1)

Safety Data

• Hazardous Substances Data: 887267-38-1(Hazardous Substances Data)

Usage

General Description

3-Chloro-2,4-difluorobenzonitrile is a chemical compound that consists of a benzene ring with a chlorine atom and two fluorine atoms attached at different positions. It is a nitrile, which means it contains a carbon triple-bonded to a nitrogen atom. 3-CHLORO-2,4-DIFLUOROBENZONITRILE is often used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It can also be used in the production of dyes and pigments. Additionally, it is important to handle this compound with care, as it can be harmful if it comes into contact with the skin, eyes, or respiratory system.

InChI:InChI=1/C7H2ClF2N/c8-6-5(9)2-1-4(3-11)7(6)10/h1-2H

Upstream product

• 2112-31-4 2,3,4-tri-chloro-benzonitrile 
• 81067-37-0 1-bromo-2,3,4-trichlorobenzene 
• 87-61-6 1,2,3-trichlorobenzene 

Downstream Products

• 154257-75-7 2,4-difluoro-3-chlorobenzoic acid 
• 1428478-97-0 di-tert-butyl (2-chloro-4-cyano-3-fluorophenyl)propanedioate 
• 1255207-37-4 3-chloro-4-(2-hydroxyethyl)-2-methoxybenzonitrile 
• 1255207-36-3 methyl (2-chloro-4-cyano-3-methoxyphenyl)acetate 
• 1255207-35-2 methyl (2-chloro-4-cyano-3-fluorophenyl)acetate 
• 1428478-96-9 (2-chloro-4-cyano-3-fluorophenyl)acetic acid 
• 1255209-32-5 tert-butyl methyl (2-chloro-4-cyano-3-fluorophenyl)malonate 

Relevant articles and documents

Synthesis method of 3-chloro-2,4-difluorobenzoic acid

The invention relates to a synthesis method of 3-chloro-2,4-difluorobenzoic acid. The method comprises: taking 1,2,3-trichlorobenzene and N-bromosuccinimide to react, taking CuCN and 1-bromo-2,3,4-trichlorobenzene to react, taking the 1-bromo-2,3,4-trichlorobenzene and KF to react and taking 3-chloro-2,4-difluorobenzonitrile and sulfuric acid to react, so as to form the 3-chloro-2,4-difluorobenzoic acid. According to the synthesis method, synthesis reaction conditions are that a reaction is carried out at normal pressure and reaction temperature fluctuates between 0 and 250 DEG C; the obtained finished product is a light yellow powdery solid and the content is more than or equal to 99.0 percent; the total mol yield of the 3-chloro-2,4-difluorobenzoic acid can reach 61.5 percent; whole reaction conditions are moderate and the method is convenient to operate and control; pressure of waste gas, waste water and waste residues is relatively low so that industrial production is facilitated.