887267-97-2

Basic information

• Product Name: 2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL
• Synonyms: 2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL;4-[5-(Trifluoromethyl)-1,3,4-oxadiazol-2-yl]biphenyl
• CAS NO: 887267-97-2
• Molecular Formula: C15H9F3N2O
• Molecular Weight: 290.2399696
• Mol File: 887267-97-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL(887267-97-2)
• EPA Substance Registry System: 2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL(887267-97-2)

Safety Data

• Hazardous Substances Data: 887267-97-2(Hazardous Substances Data)

Upstream product

• 92-91-1 biphenyl-4-acetaldehyde 

Relevant articles and documents

Diazotrifluoroethyl Radical: A CF3-Containing Building Block in [3 + 2] Cycloaddition

We present herein a visible-light-induced [3 + 2] cycloaddition of a hypervalent iodine(III) reagent with α-ketoacids for the construction of 5-CF3-1,3,4-oxadiazoles that are of importance in medicinal chemistry. The reaction proceeds smoothly without a photocatalyst, metal, or additive under mild conditions. Different from the well-established trifluorodiazoethane (CF3CHN2), the diazotrifluoroethyl radical [CF3C(·)N2], a trifluoroethylcarbyne (CF3C?:) equivalent and an unusual CF3-containing building block, is involved in the present reaction system.