887569-13-3 Usage
Description
4-Fluoro-6-Methoxy-1H-indazole is a synthetic indazole derivative with the molecular formula C9H8FN2O. It features a fluorine atom and a methoxy group attached to the indazole ring, which contributes to its potential applications in medicinal chemistry and drug development.
Uses
Used in Medicinal Chemistry:
4-Fluoro-6-Methoxy-1H-indazole is used as a research chemical for exploring its pharmacological effects on the central nervous system. Its unique structure allows for investigation into various biological activities and potential therapeutic applications.
Used in Drug Development:
As a precursor in the synthesis of other compounds, 4-Fluoro-6-Methoxy-1H-indazole plays a crucial role in drug development. Its chemical properties can be harnessed to create new molecules with improved pharmacological profiles, enhancing the discovery of novel therapeutic agents.
Safety Precautions:
When working with 4-Fluoro-6-Methoxy-1H-indazole, it is essential to follow proper handling and safety procedures to minimize risks associated with chemical exposure. This includes the use of appropriate personal protective equipment and adherence to laboratory safety guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 887569-13-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,5,6 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 887569-13:
(8*8)+(7*8)+(6*7)+(5*5)+(4*6)+(3*9)+(2*1)+(1*3)=243
243 % 10 = 3
So 887569-13-3 is a valid CAS Registry Number.
887569-13-3Relevant articles and documents
Development of a late-stage diversification strategy for the 4- And 5-Positions of 4,5,6-trisubstituted indazoles
Barber, Joyann S.,Burtea, Alexander,Collins, Michael R.,Tran-Dube, Michelle,Patman, Ryan L.,Scales, Stephanie,Smith, Graham,Spangler, Jillian E.,Wang, Fen,Wang, Wei,Yang, Shouliang,Zhu, JinJiang,Patrick Montgomery
, p. 9047 - 9052 (2020)
Indazoles represent a privileged motif in drug discovery. However, the formation of highly substituted indazoles can require the execution of lengthy synthetic routes with minimal opportunities to introduce diversity. In this report, we disclose the development of a late-stage diversification strategy for the 4- and 5-positions of 4,5,6-trisubstituted indazoles. A regioselective C-H functionalization and subsequent nucleophilic aromatic substitution provide two sequential points of diversification. The synthetic sequence delivers rapid access to an array of 4,5,6-trisubstituted indazoles in only four steps from readily available starting materials.
