887590-25-2

Basic information

• Product Name: 3,4-DIHYDRO-2H-QUINOXALINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 3,4-DIHYDRO-2H-QUINOXALINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;tert-Butyl 3,4-dihydroquinoxaline-1(2H)-carboxylate;TERT-BUTYL1,2,3,4-TETRAHYDROQUINOXALINE-1-CARBOXYLATE
• CAS NO: 887590-25-2
• Molecular Formula: C₁₃H₁₈N₂O₂
• Molecular Weight: 234.29
• Product Categories: pharmacetical
• Mol File: 887590-25-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 345.3°C at 760 mmHg
• Flash Point: 162.6°C
• Appearance: /
• Density: 1.112g/cm³
• Vapor Pressure: 6.22E-05mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: 2-8°C(protect from light)
• PKA: 3.27±0.70(Predicted)
• CAS DataBase Reference: 3,4-DIHYDRO-2H-QUINOXALINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIHYDRO-2H-QUINOXALINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(887590-25-2)
• EPA Substance Registry System: 3,4-DIHYDRO-2H-QUINOXALINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(887590-25-2)

Safety Data

• Hazardous Substances Data: 887590-25-2(Hazardous Substances Data)

Usage

General Description

3,4-Dihydro-2H-quinoxaline-1-carboxylic acid tert-butyl ester is a chemical compound with the molecular formula C15H19N2O2. It is a tert-butyl ester derivative of quinoxaline-1-carboxylic acid, and it is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 3,4-DIHYDRO-2H-QUINOXALINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is a white to off-white powder with a molecular weight of 265.32 g/mol. It is considered to be a potentially hazardous chemical and should be handled with care in a controlled laboratory environment.

InChI:InChI=1/C13H18N2O2/c1-13(2,3)17-12(16)15-9-8-14-10-6-4-5-7-11(10)15/h4-7,14H,8-9H2,1-3H3

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 59564-59-9 1,2,3,4-tetrahydroquinoxalin-2-one 
• 1441005-75-9 C₁₃H₁₉BrN₂O₂ 
• 459817-82-4 2,2-dioxo-[1,2,3]oxathiazolidine-3-carboxylic acid tert-butyl ester 
• 615-36-1 2-bromoaniline 
• 3476-89-9 1,2,3,4-tetrahydroquinoxaline 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1304598-85-3 tert-butyl 4-(4-(methoxycarbonyl)benzyl)-3,4-dihydroquinoxaline-1(2H)-carboxylate 
• 1304598-38-6 C₂₀H₂₁N₃O₆ 
• 1304598-63-7 C₁₅H₁₃N₃ 
• 1304598-51-3 C₁₆H₁₅N₃O₄ 
• 1304598-48-8 C₁₅H₁₃N₃O₄ 
• 1304599-06-1 C₂₇H₂₇N₇O₂ 
• 1304599-02-7 C₁₉H₁₈N₄O 
• 1000688-56-1 N-Cyclopropyl-4-{4-[3-(1H-pyrazol-4-yl)pyrrolidine-1-carbonyl]-3,4-dihydro-2H-quinoxalin-1-ylmethyl}benzamide 
• 1000688-43-6 4-{4-[3-(1H-Pyrazol-4-yl)pyrrolidine-1-carbonyl]-3,4-dihydro-2H-quinoxalin-1-ylmethyl}benzoic acid 
• 1000688-20-9 4-{4-[3-(1H-Pyrazol-4-yl)pyrrolidine-1-carbonyl]-3,4-dihydro-2H-quinoxalin-1-ylmethyl}benzoic acid methyl ester 
• 1000687-52-4 N-Cyclopropyl-4-{4-[3-(1H-pyrazol-4-yl)pyrrolidine-1-carbonyl]-3,4-dihydro-2H-quinoxalin-1-yl}benzamide 
• 1000688-14-1 4-{4-[3-(1H-Pyrazol-4-yl)pyrrolidine-1-carbonyl]-3,4-dihydro-2H-quinoxalin-1-yl}benzamide 
• 1304598-78-4 C₁₈H₁₉N₃O 
• 1000688-85-6 4-(3,4-dihydroquinoxalin-1(2H)-yl)benzoic acid 

Relevant articles and documents

TETRAHYDROQUINOLINE SUBSTITUTED HYDROXAMIC ACIDS AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS

Histone deacetylases inhibitors (HDACIs) and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC provides a benefit, like a cancer, a neurodegenerative disorder, a neurological disease, tr

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The synthesis of dihydrobenzo[1,4]oxazines has been accomplished efficiently by copper catalyzed intramolecular cyclization of the adducts formed by the treatment of 1,2-cyclic sulfamidates with 2-halo phenols. The products (except two) are new and their yields are high. The catalyst is easily available and less expensive.