888734-44-9Relevant articles and documents
Differential inhibition of group IVA and group VIA phospholipases A 2 by 2-oxoamides
Stephens, Daren,Barbayianni, Efrosini,Constantinou-Kokotou, Violetta,Peristeraki, Anna,Six, David A.,Cooper, Jennifer,Harkewicz, Richard,Deems, Raymond A.,Dennis, Edward A.,Kokotos, George
, p. 2821 - 2828 (2006)
Inhibitors of the Group IVA phospholipase A2 (GIVA CPLA 2) and GVIA iPLA2 are useful tools for defining the roles of these enzymes in cellular signaling and inflammation. We have developed inhibitors of GVIA iPLA2/su