889945-56-6

Basic information

• Product Name: 1-benzyl-3,5-difluorobenzene
• Synonyms: 1-benzyl-3,5-difluorobenzene
• CAS NO: 889945-56-6
• Molecular Weight: 204.219
• Mol File: 889945-56-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-benzyl-3,5-difluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3,5-difluorobenzene(889945-56-6)
• EPA Substance Registry System: 1-benzyl-3,5-difluorobenzene(889945-56-6)

Safety Data

• Hazardous Substances Data: 889945-56-6(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 156545-07-2 3,5-difluorophenylboronic acid 
• 100-39-0 benzyl bromide 

Relevant articles and documents

Synthesis, structure, and catalytic applications for ortho - And meta -carboranyl based NBN pincer-Pd complexes

o- and m-Carborane-based NBN pincer palladium complexes (oCB-L1)Pd, (oCB-L2)Pd, and (mCB-L1)Pd are synthesized in two steps from commercially available starting materials. The pincer complexes were prepared by the reaction of bis-[R(hydroxy)methyl]-1,2-dicarba-closo-dodecaborane (R = 2-pyridyl oCB-L1, 6-methyl-2-pyridyl oCB-L2) or bis-[2-pyridyl (hydroxy)methyl]-1,2-dicarba-meta- dodecaborane (mCB-L1) with [PdCl2(MeCN)2] under mild conditions. The X-ray structure determination of all carboranyl pincer complexes shows unambiguously B-H activation of the carborane cages. The results agree with the Pd-B bonds in all complexes exhibiting strong σ-electron donation. Theoretical calculations reveal the importance of considering the solid state intermolecular hydrogen bonding when investigating the trans influence in organometallic chemistry. A localized orbitals approach has also been applied to analyze the metal oxidation state in the carboranyl pincer complexes. Catalytic applications of (oCB-L1)Pd and (mCB-L1)Pd have shown the complexes are good catalyst precursors in Suzuki coupling in water and with very low amounts of catalyst loadings.

Suzuki-miyaura cross-couplings mediated by trans-PdBr(N-Succ)(PPh 3)2: A convenient synthetic method for diarylmethanes and aryl(heteroaryl)- methanes

Diarylmethanes can be accessed efficiently by Suzuki-Miyaura cross-couplings of arylboronic acids with benzyl halides mediated by trans-PdBr(N-Succ) (PPh3)2. The methodology can be applied to the synthesis of aryl(heteroaryl)methanes. Georg Thieme Verlag Stuttgart New York.