89167-24-8

Basic information

• Product Name: 6-BROMO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE
• Synonyms: 6-BROMO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE;6-BroMo[1,2,4]triazol[1,5-A]pyriMidine;6-broMo-[1,2,4]triazolo[1,5-a]pyri;[1,2,4]Triazolo[1,5-a]pyrimidine,6-bromo-
• CAS NO: 89167-24-8
• Molecular Formula: C₅H₃BrN₄
• Molecular Weight: 199.02
• Mol File: 89167-24-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Density: 2.13±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 6-BROMO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE(89167-24-8)
• EPA Substance Registry System: 6-BROMO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE(89167-24-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 89167-24-8(Hazardous Substances Data)

Usage

General Description

6-Bromo[1,2,4]triazolo[1,5-a]pyrimidine is a chemical compound with a fused heterocyclic ring structure. It is a pyrimidine derivative containing a bromine atom and a triazolo ring system. 6-BROMO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE has potential applications in pharmaceutical chemistry, particularly in the development of new drugs and bioactive molecules due to its unique structure and reactivity. Additionally, it may exhibit biological activity and could be used as a building block in the synthesis of other organic compounds. Further research and investigation into the properties and potential uses of 6-Bromo[1,2,4]triazolo[1,5-a]pyrimidine are necessary to fully understand its capabilities and applications.

Upstream product

• 2065-75-0 2-Bromo-malonaldehyde 
• 61-82-5 4H-1,2,4-triazol-3-amine 
• 21577-50-4 mucobromic acid 
• 61-82-5 3⁽⁵⁾-amino-1,2,4-triazole 
• 61-82-5 3-amino-1,2,4-triazole 

Downstream Products

• 1252803-83-0 6-(3,4-dichlorophenylmethyl)amino-[1,2,4]triazolo[1,5-a]pyrimidine 
• 1421684-99-2 3-([1,2,4]triazolo[1,5-a]pyrimidin-6-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)-phenyl)benzamide 
• 1407999-95-4 C₂₈H₂₇F₃N₁₀O 

Relevant articles and documents

ErbB RECEPTOR INHIBITORS AS ANTI-TUMOR AGENTS

Provided herein are novel compounds as inhibitors of type I receptor tyrosine kinases, the pharmaceutical compositions comprising one or more of the compounds and salts thereof as an active ingredient, and the use of the compounds and salts thereof in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals and especially in humans.

A new route for the synthesis of 6-substituted [1,2,4]triazolo[4,3-a] pyrimidines

A new method of generating the fused heterocyclic system with bridgehead nitrogen, triazolo[4,3-a]pyrimidine, from 3-amino-1,2,4-triazole and unsaturated halo acids has been described.

METABOTROPIC GLUTAMATE RECEPTOR MODULATORS

The invention relates to heterocyclic derivatives as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are mGluR5 modulators and are therefore useful for the control and prevention of acute and/or chronic neurological disorders