89270-28-0 Usage
Description
Cyclosporine metabolite M17 is a derivative of the immunosuppressive drug cyclosporine, which is characterized by its white solid appearance. It is known for its specific inhibitory effects on the growth of renal cells in culture, making it a potentially valuable compound in the field of medicine.
Uses
Used in Pharmaceutical Industry:
Cyclosporine metabolite M17 is used as a research compound for studying its inhibitory effects on renal cell growth. This application is crucial for understanding the underlying mechanisms of renal cell proliferation and identifying potential therapeutic targets for the treatment of kidney-related diseases.
Used in Biomedical Research:
In the field of biomedical research, cyclosporine metabolite M17 serves as a valuable tool for investigating the role of specific cellular pathways and mechanisms involved in renal cell growth regulation. Its use can contribute to the development of novel therapeutic strategies for managing renal disorders and improving patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 89270-28-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,2,7 and 0 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 89270-28:
(7*8)+(6*9)+(5*2)+(4*7)+(3*0)+(2*2)+(1*8)=160
160 % 10 = 0
So 89270-28-0 is a valid CAS Registry Number.
InChI:InChI=1/C62H111N11O13/c1-24-43-58(82)67(17)33-48(75)68(18)44(29-34(2)3)55(79)66-49(38(10)11)61(85)69(19)45(30-35(4)5)54(78)63-41(15)53(77)64-42(16)57(81)70(20)46(31-36(6)7)59(83)71(21)47(32-37(8)9)60(84)72(22)50(39(12)13)62(86)73(23)51(56(80)65-43)52(76)40(14)27-25-26-28-74/h25-26,34-47,49-52,74,76H,24,27-33H2,1-23H3,(H,63,78)(H,64,77)(H,65,80)(H,66,79)/b26-25+/t40-,41+,42-,43+,44?,45+,46-,47+,49?,50?,51?,52-/m1/s1
89270-28-0Relevant articles and documents
Synthesis of the Main Metabolite (OL-17) of Cyclosporin A
Eberle, Marcel K.,Nuninger, Francois
, p. 2689 - 2691 (1992)
Acetyl-cyclosporin A (2) was subjected to the conditions of allylic radical bromination to give 3.Exchange of the bromide by acetoxy led to 4 which was hydrolyzed to the known metabolite OL-17 (5) of cyclosporin A (1).
