89281-44-7 Usage
General Description
5-Thiazolamine, 2-methyl- is a chemical compound with the molecular formula C4H6N2S. It is a member of the thiazole family, which is known for its diverse biological and pharmacological activities. 5-Thiazolamine, 2-methyl- is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also an important intermediate in the production of dyes and other organic compounds. This chemical is known for its potent antimicrobial and antifungal properties, making it a valuable component in the development of new drugs and treatments. Additionally, it is a colorless liquid with a strong odor, and it is highly flammable, requiring careful handling and storage. Overall, 5-Thiazolamine, 2-methyl- is a versatile and important chemical compound with a wide range of applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 89281-44-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,2,8 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 89281-44:
(7*8)+(6*9)+(5*2)+(4*8)+(3*1)+(2*4)+(1*4)=167
167 % 10 = 7
So 89281-44-7 is a valid CAS Registry Number.
89281-44-7Relevant articles and documents
Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancer
Scott, David A.,Aquila, Brian M.,Bebernitz, Geraldine A.,Cook, Donald J.,Dakin, Les A.,Deegan, Tracy L.,Hattersley, Maureen M.,Ioannidis, Stephanos,Lyne, Paul D.,Omer, Charles A.,Ye, Minwei,Zheng, XiaoLan
scheme or table, p. 4794 - 4797 (2009/05/30)
The bisamide class of kinase inhibitors was identified as being active against CSF-1R. The synthesis and SAR of pyridyl and thiazolyl bisamides are reported, along with the pharmacokinetic properties and in vivo activity of selected examples.
Imidazopyrazines as protein kinase inhibitors
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Page/Page column 171, (2010/11/27)
In its many embodiments, the present invention provides a novel class of imidazopyrazine compounds as inhibitors of protein and/or checkpoint kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or checkpoint kinases using such compounds or pharmaceutical compositions.