89379-40-8

Basic information

• Product Name: 1-DIMETHYLAMINO-2-METHYL-2-AMINOPROPANE
• Synonyms: TIMTEC-BB SBB008492;1-DIMETHYLAMINO-2-METHYL-2-AMINOPROPANE;N1,N1,2,2-Tetramethylethylenediamine;1,2-propanediamine, N~1~,N~1~,2-trimethyl-;N~1~,N~1~,2-trimethylpropane-1,2-diamine hydrochloride;(2-amino-2-methylpropyl)dimethylamine(SALTDATA: 2.05HCl 0.2H2O);(2-amino-2-methyl-propyl)-dimethyl-amine
• CAS NO: 89379-40-8
• Molecular Formula: C₆H₁₆N₂
• Molecular Weight: 116.2
• Mol File: 89379-40-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 126.2 °C at 760 mmHg
• Flash Point: 26.5 °C
• Appearance: /
• Density: 0.838 g/cm³
• Vapor Pressure: 11.8mmHg at 25°C
• Refractive Index: 1.447
• CAS DataBase Reference: 1-DIMETHYLAMINO-2-METHYL-2-AMINOPROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-DIMETHYLAMINO-2-METHYL-2-AMINOPROPANE(89379-40-8)
• EPA Substance Registry System: 1-DIMETHYLAMINO-2-METHYL-2-AMINOPROPANE(89379-40-8)

Safety Data

• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 2735
• HazardClass: IRRITANT
• Hazardous Substances Data: 89379-40-8(Hazardous Substances Data)

Usage

Uses

(2-Amino-2-methylpropyl)dimethylamine is used as a reactant in the preparation and structure activity relationships of angular benzophenazine dual topoisomerase I and topoisomerase II inhibitors as anticancer agents.

InChI:InChI=1/C6H16N2/c1-6(2,7)5-8(3)4/h5,7H2,1-4H3

Upstream product

• 62983-26-0 2-Amino-N',N'-dimethylisobutyramid 
• 19155-54-5 1-Dimethylamino-2-methyl-2-nitro-propan 
• 91447-49-3 dimethyl-(β-nitro-isobutyl)-amine; hydrochloride 

Downstream Products

• 175866-20-3 3-Cyclohexyl-5-ethoxy-1,3-dihydro-1-[2-methoxy-4-[N-(2-dimethylamino-1,1-dimethylethyl)carbamoyl]benzyl]-2H-benzimidazol-2-one 

Relevant articles and documents

2-PHENYL-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN TYROSINE KINASE ROR1 ACTIVITY

A compound of formula (I′) or (I′′) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of mammalian kinase enzyme activity, including ROR1 tyrosine kinase activity and may be used in the treatment of disorders associated with such activity.

1-(2-Methyl-2-propenyl)-3-(4-methyl-3-pentenyl)-Δ3 -cyclohexene-1-carboxaldehyde and 1-(2-methyl-2-propenyl)-4-(4-methyl-3-pentenyl)-Δ3 -cyclohexene-1-carboxaldehyde

Described are the compounds 1-(2-methyl-2-propenyl)-3-(4-methyl-3-pentenyl)-Δ3 -cyclohexene-1-carboxaldehyde and 1-(2-methyl-2-propenyl)-4-(4-methyl-3-pentenyl)-Δ3 -cyclohexene-1-carboxaldehyde; and a process for preparing same by means of reacting a methallylic halide with a mixture of 3 and 4-(4-methyl-3-pentenyl)-Δ3 -cyclohexene-1-carboxaldehyde using a phase transfer agent in a two phase system according to the reaction: STR1 wherein the carboxaldehyde moiety is bonded to the alpha-carbon atom or the beta-carbon atom, X is chloro or bromo and M is alkali metal, processes for adding such 1-(2-methyl-2-propenyl)-(4-methyl-3-pentenyl)-Δ3 -cyclohexene-1-carboxaldehydes to consumable materials whereby: I. In foodstuffs and medicinal products, floral, muguet, coriander, fatty, green and creamy aroma and flavor characteristics are augmented or enhanced; Ii. In perfumes and perfumed articles, citrus, floral and fatty nuances are imparted, augmented and/or enhanced; and Iii. In tobaccos and tobacco flavor and aroma imparting or enhancing compositions, sweet, spicey, coriander-like, citrus/fruity notes are imparted, prior to, and, on smoking And tobacco, foodstuff, flavor and perfume compositions containing the 1-(2-methyl-2-propenyl)-(4-methyl-3-pentenyl)-Δ3 -cyclohexene-1-carboxaldehydes.