893842-26-7 Usage
Description
5,5-diMethyl-2-(2,2,2-trifluoroacetyl)cyclohexane-1,3-dione is a chemical compound with the molecular formula C11H13F3O3. It is a derivative of cyclohexanedione, with two methyl groups and a trifluoroacetyl group attached to the cyclohexane ring. 5,5-diMethyl-2-(2,2,2-trifluoroacetyl)cyclohexane-1,3-dione is known for its unique chemical properties and is commonly used in organic synthesis and chemical research.
Uses
Used in Organic Synthesis:
5,5-diMethyl-2-(2,2,2-trifluoroacetyl)cyclohexane-1,3-dione is used as a precursor in the preparation of various other organic compounds. Its unique structure allows for the formation of a wide range of products, making it a valuable building block in the synthesis of complex organic molecules.
Used in Chemical Research:
5,5-diMethyl-2-(2,2,2-trifluoroacetyl)cyclohexane-1,3-dione is also used as a reagent in chemical reactions, enabling researchers to study its properties and behavior under different conditions. Its versatility in chemical reactions makes it a valuable tool for understanding various chemical processes and mechanisms.
Used in Pharmaceutical Applications:
5,5-diMethyl-2-(2,2,2-trifluoroacetyl)cyclohexane-1,3-dione has been studied for its potential biological activities, which may lead to its use in the development of new pharmaceuticals. Its unique structure and properties make it a promising candidate for further research and development in the field of drug discovery.
Used in Chemical Industry:
In the chemical industry, 5,5-diMethyl-2-(2,2,2-trifluoroacetyl)cyclohexane-1,3-dione can be utilized in the production of various chemicals and materials. Its unique properties and reactivity make it a valuable component in the synthesis of a wide range of products, contributing to the advancement of the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 893842-26-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,3,8,4 and 2 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 893842-26:
(8*8)+(7*9)+(6*3)+(5*8)+(4*4)+(3*2)+(2*2)+(1*6)=217
217 % 10 = 7
So 893842-26-7 is a valid CAS Registry Number.
893842-26-7Relevant articles and documents
Discovery, structure-activity relationship studies, and anti-nociceptive effects of 1-phenyl-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one as novel opioid receptor agonists
Cheng, Ming-Fu,Ou, Li-Chin,Chen, Shu-Chun,Chang, Wan-Ting,Law, Ping-Yee,Loh, Horace H.,Chao, Yu-Sheng,Shih, Chuan,Yeh, Shiu-Hwa,Ueng, Shau-Hua
, p. 4694 - 4703 (2014/10/15)
The μ-opioid receptor (MOR) is the major opioid receptor targeted by most analgesics in clinical use. However, the use of all known MOR agonists is associated with severe adverse effects. We reported that the 1-phenyl-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-ones are novel opioid receptor agonists. Subsequent structural modification resulted in the potent MOR/KOR (κ-opioid receptor) agonists 19, 20, and 21. Testing the analgesic effect of these in WT B6 mice (tail-flick test) gave ED50 values of 8.4, 10.9, and 26.6 mg/kg, respectively. The 1-phenyl-3,6,6-trimethyl-1,5,6,7- tetrahydro-4H-indazol-4-one core could be addressed in 1 or 2 synthetic steps with moderate to high percent of yield. In the adenylyl cyclase assay, compound 19 displayed a MOR/KOR agonist profile, with IC50 values of 0.73 and 0.41 μM, respectively. Current results suggest that compound 19 is a promising lead to go further development and in vitro/in vivo adverse effects studies.
