89488-30-2

Basic information

• Product Name: 5-BROMO-2-HYDROXY-3-PICOLINE
• Synonyms: 5-BROMO-3-METHYL-PYRIDIN-2-OL;5-BROMO-3-METHYL-2-PYRIDINOL;5-BROMO-3-METHYL-2-PYRIDONE;5-BROMO-2-HYDROXY-3-METHYLPYRIDINE;5-BROMO-2-HYDROXY-3-PICOLINE;2-HYDROXY-5-BROMO-3-PICOLINE;2-Hydorxy-5-Bromo-3-Picoline;5-BROMO-2-HYDROXY-3-PICOLINE (5-BROMO-2-HYDROXY-3-METHYLPYRIDINE)
• CAS NO: 89488-30-2
• Molecular Formula: C₆H₆BrNO
• Molecular Weight: 188.02
• Product Categories: Pyridine;Halides;Pyridines;Bromopyridines;Halopyridines;C6Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks
• Mol File: 89488-30-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 170-174 °C(lit.)
• Boiling Point: 326.213 °C at 760 mmHg
• Flash Point: 151.088 °C
• Appearance: Off-white/Solid
• Density: 1.5296 (rough estimate)
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.5500 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: soluble in Methanol
• PKA: 10.55±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-2-HYDROXY-3-PICOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-HYDROXY-3-PICOLINE(89488-30-2)
• EPA Substance Registry System: 5-BROMO-2-HYDROXY-3-PICOLINE(89488-30-2)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-38-41-36/37/38
• Safety Statements: 36/37/39-36-26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 89488-30-2(Hazardous Substances Data)

Usage

Chemical Properties

creamish to light brown crystalline powder

InChI:InChI=1/C6H6BrNO/c1-4-2-5(7)3-8-6(4)9/h2-3H,1H3,(H,8,9)

Upstream product

• 3430-21-5 5-bromo-3-methyl-pyridin-2-ylamine 

Downstream Products

• 29241-60-9 5-bromo-2-chloro-3-methylpyridine 
• 1425045-01-7 1,3-dimethyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyridin-2-one 

Relevant articles and documents

PYRIDINONE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS

The invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Heterocyclic substituted aminoazacycles useful as central nervous system agents

Heterocyclic substituted aminoazacyclic compounds of the formula (I):Z-R3, wherein Z is a defined aminoazacycle and R3 is a defined heterocycle moiety, pharmaceutical compositions of these compounds, and use of said compositions to control synaptic transmission in mammals.